Extragonadal primordial germ cells or placental progenitor cells?

Reprod Biomed Online

Department of Cell and Regenerative Biology, University of Wisconsin-Madison School of Medicine and Public Health, 1300 University Avenue, Madison, WI 53706, USA. Electronic address:

Published: January 2018

Primordial germ cells (PGCs), the precursors of the gametes, are now claimed to segregate within the extra-embryonic tissues of three species of placental mammals. In this brief Commentary, I raise the question of whether the so-called PGCs are not PGCs at all, but rather, progenitor cells that build the fetal-placental interface in Placentalia.

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http://dx.doi.org/10.1016/j.rbmo.2017.09.013DOI Listing

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