Generally accepted indications for minimally invasive surgery (MIS) approach to thymic tumours include small, well encapsulated non-invasive tumours. MIS for more advanced complicated thymic tumours remain controversial. This is due to concerns on whether an oncologically complete resection can be done. However with increased experience MIS can be used safely in a selected group of complex thymic tumours without oncological compromise.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637989PMC
http://dx.doi.org/10.21037/jovs.2017.03.27DOI Listing

Publication Analysis

Top Keywords

thymic tumours
16
minimally invasive
8
invasive surgery
8
tumours
5
limits extreme
4
extreme minimally
4
surgery invasive
4
thymic
4
invasive thymic
4
tumours generally
4

Similar Publications

Introduction: Complete radical resection is crucial for successfully treating thymic carcinomas. However, when the invasion of the great vessels or the heart in Masaoka III and IV stages occurs, the management poses more challenges. The R0 resection often requires neoadjuvant treatment.

View Article and Find Full Text PDF

Otherwise, inoperable. The role of ECMO in thoracic surgery - focus on the mediastinum.

Port J Card Thorac Vasc Surg

January 2025

Thoracic surgeon, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

The use of extracorporeal membrane oxygenation (ECMO) in surgery is expanding as the medical community started adopting it, with good results, for procedures with high risk of respiratory and hemodynamic instability. This technique provided the possibility to reduce the number of patients previously considered inoperable because of these limitations. Thymic epithelial tumors (TETs) are rare neoplastic mediastinal lesions, with a reported incidence of 0.

View Article and Find Full Text PDF

While highly morbid forms of chronic graft versus host disease (cGVHD) and severe late effects of allogeneic hematopoietic cell transplant (HCT) can impact children and adults alike, unique considerations arise in pediatric cases regarding diagnosis, monitoring, treatment, and likelihood of resolution. As children can present with atypical features of cGVHD, and with more significant disease due to inability to communicate symptoms, they may be at increased risk for highly morbid forms of cGVHD and incur greater subsequent late effects, which may be more pronounced in those with underlying chromosomal breakage syndromes, with higher prevalence in pediatric HCT recipients. The long-term effects of cGVHD and its therapies include impaired immune reconstitution, leading to increased risks of infection and secondary malignant neoplasms.

View Article and Find Full Text PDF

Background: Neuroendocrine tumors of the thymus (NETT) are rare and malignant tumors that arise in the anterior mediastinum. These tumors can exhibit aggressive behavior and may involve surrounding critical structures, such as the superior vena cava. This case contributes to the literature by presenting a recurrent thymic carcinoma with invasion of major blood vessels, including the superior vena cava, and the complexities involved in its surgical management.

View Article and Find Full Text PDF

T cells, as integral components of the adaptive immune system, recognize diverse antigens through unique T cell receptors (TCRs). To achieve this, during T cell maturation, the thymus generates a wide repertoire of TCRs. This is essential for understanding cancer evolution, progression, and the efficacy of immunotherapies.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!