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Objective: To evaluate the current evidence and to identify associated risk factors that increase the incidence of this complication. Fluoroquinolone (FQ) has been considered the first-line therapy for uncomplicated urinary infections. FQ has been associated with Achilles tendon disorders, especially during the first month of treatment.
Methods: Data sources searched included PubMed, MEDLINE, and Scopus from January 1988 to June 2017.
Results: A total of 79 articles were used, with ciprofloxacin representing the most common drug.
Conclusion: We found that male gender, advanced age, normal body mass index, chronic renal failure, and concurrent use of corticosteroids increase the risk of Achilles tendon disorders.
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| http://dx.doi.org/10.1016/j.urology.2017.10.017 | DOI Listing |
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