Chemical Constituents from the Flower of Hosta plantaginea with Cyclooxygenases Inhibition and Antioxidant Activities and Their Chemotaxonomic Significance.

Two new phenolic glucosides, hostaflavanone A () and -1-phenylpropane-1,2-diol-2--β-d-glucopyranoside (), together with six known compounds, -1-phenylpropane-1,2-diol (), phenethyl--β-d-glucopyranoside (), phenethanol-β-d-gentiobioside (), phenethyl--rutinoside (), (1, 3)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (), and (1, 3)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (), were isolated from the flower of , and their structures were elucidated by nuclear magnetic resonance (NMR), high resolution electrospray ionization mass spectroscopy (HRESIMS), and circular dichroism (CD) analyses. The cyclooxygenases (COX-1 and COX-2) inhibition and antioxidant activities of compounds and - were investigated, and they showed moderate cyclooxygenases inhibition activities. Moreover, only compound exhibited moderate antioxidant activity, with an IC value of 83.2 μM, while - showed insignificant activity with IC values of 282, 257, and 275 μM, respectively. This is the first report of compounds and - from the Liliaceae family. The chemotaxonomic significance of the isolated compounds was also summarized.