A culture based on quality and excellence is the cornerstone to a successful healthcare system. Padeh-Poriya Medical Center integrates clinical activity with extensive research, including basic research, clinical research and research in the field of nursing, while ensuring high standards expressed in the accreditation survey of the Joint Commission International, national quality indicators and patient satisfaction surveys of the Ministry of Health. As a general medical center, it provides medical services to residents of the Galilee, along with continuous development and improvement in quality and range, as well as implementation of new technologies. The establishment of the Faculty of Medicine in the Galilee contributed to the expansion of academic and research activities through the foundation of the Research Unit and the Advanced Research Institute. The current issue presents part of the clinical and research activities lead by the Medical Center staff, which express the quality, excellence and academic culture.
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Centro di Ricerca e Innovazione sulle Patologie Surrenaliche, AOU Careggi, Florence, Italy.
Purpose: To compare functional deficits associated to surgery with those caused by the growth of the head and neck paragangliomas (HNPGLs).
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Ferroptosis triggers mitochondrial fragmentation via Drp1 activation.
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CECAD Cluster of Excellence, University of Cologne, Cologne, Germany.
Constitutive mitochondrial dynamics ensure quality control and metabolic fitness of cells, and their dysregulation has been implicated in various human diseases. The large GTPase Dynamin-related protein 1 (Drp1) is intimately involved in mediating constitutive mitochondrial fission and has been implicated in mitochondrial cell death pathways. During ferroptosis, a recently identified type of regulated necrosis driven by excessive lipid peroxidation, mitochondrial fragmentation has been observed.
View Article and Find Full Text PDFAdherence to tuberculosis (TB) treatment in high compared to low TB burden countries: study protocol for a systematic review and meta-analysis with a qualitative meta-synthesis of themes.
BMJ Open
January 2025
Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
Introduction: Non-adherence to tuberculosis (TB) treatment poses a significant challenge to effective TB management globally and is a major contributor to the emergence of multidrug-resistant TB. Although adherence to TB treatment has been widely studied, a comprehensive evaluation of the comparative levels of adherence in high- versus low-TB burden settings remains lacking. The objective of this systematic review and meta-analysis is to assess the levels of adherence to TB treatment in high-TB burden countries compared to low-burden countries.
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Multiple Sclerosis Center of Excellence West, Veterans Affairs, USA; Rehabilitation Care Service, VA Puget Sound Health Care System, 1660 S Columbian Way, Seattle, Washington, 98108, USA; Department of Rehabilitation Medicine, University of Washington, 325 9th Avenue, Seattle, Washington, 98104, USA. Electronic address:
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US FDA, Silver Spring, MD, USA.
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