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Patterns of serum lipids derangements and cardiovascular risk assessment in patients with primary biliary cholangitis.
Ann Hepatol
September 2020
Department of Endocrinology, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Mexico.
Article Synopsis
- - Primary biliary cholangitis (PBC) is a chronic autoimmune disease that affects cholesterol metabolism, prompting researchers to study lipid abnormalities and cardiovascular event risks in affected patients from 2000 to 2009 compared to healthy controls.
- - The study involved 54 PBC patients and 106 controls, revealing significant differences in cholesterol levels, with higher instances of hypercholesterolemia and elevated LDL in PBC patients, while HDL levels were also elevated.
- - Despite the lipid abnormalities in PBC patients, the overall 10-year cardiovascular risk was similar between PBC patients and controls, with only one cardiovascular event (a stroke) reported during an average follow-up of about 58 months.
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