In vitro efficacy of Duddingtonia flagrans against nematodes of sheep based on in vivo calculations.

Rev Bras Parasitol Vet

Laboratório de Biologia Celular e Tecidual, Centro de Biociências e Biotecnologia - CBB, Universidade Estadual do Norte Fluminense - UENF, Campos dos Goytacazes, RJ, Brasil.

Published: February 2019

Duddingtonia flagrans has been tested as an alternative parasite control, but data from in vitro experiments based on in vivo calculations describing nematophagous fungi predation in nematodes are restricted. The objective of this work was to determine the efficacy of D. flagrans against sheep nematode larvae in vitro using in vivo calculations. Fecal samples were introduced to fungi in different concentrations: 0.0/control; 0.05; 0.1; 0.2; 0.4; 0.8; 1.6; 3.2; and 6.4 g corresponding, respectively, to 583.000; 1.166.000; 2.332.000; 4.664.000; 9.328.000; 18.656.000; 37.312.000 and 74.624.000 chlamydospores/kg of body weight. The material was incubated for 14 days, before the larvae recovery (Assay 1). Assay 2 was carried out with the doses of 0.00625; 0.0125; and 0.025 g. The results showed a negative correlation between fungal concentrations and larval numbers for both assays. The fungus demonstrated an efficacy above 89% in both assays. Thus, we consider that the data from in vitro studies based on in vivo calculations may optimize the fungi quantities for field experiments.

Download full-text PDF

Source
http://dx.doi.org/10.1590/S1984-29612017050DOI Listing

Publication Analysis

Top Keywords

vivo calculations
16
based vivo
12
duddingtonia flagrans
8
data vitro
8
vitro
4
vitro efficacy
4
efficacy duddingtonia
4
flagrans nematodes
4
nematodes sheep
4
sheep based
4

Similar Publications

Background: Knowledge of the chemical composition of amyloid plaques and tau tangles at the earlier stages of Alzheimer's disease (AD) pathology is sparse. This is due to limited access to human brain during life and at the earlier stages of AD pathophysiology and technical limitations in quantifying amyloid and tau species at a subcellular level. Understanding the chemical composition of plaques and tangles, how rapidly they grow and what factors drive growth is important for developing and refining therapeutics.

View Article and Find Full Text PDF

Background: Intracranial atherosclerosis is a common age-related neuropathology that has been linked to cognitive decline and dementia and often mixed with Alzheimer's and other neuropathologies. But the association of atherosclerosis with brain morphometric abnormalities has not been explored. This work combined Deformation-based morphometry on ex-vivo MRI with detailed neuropathological examination in a large number of community-based older adults to investigate the association.

View Article and Find Full Text PDF

Background: Evidence is accumulating that cerebral small vessel disease may contribute to neurodegeneration. Brain arteriolosclerosis, a prominent type of small vessel disease in the aging brain, is associated with cognition. Using a previously developed published automated in-vivo MRI classifier for arteriolosclerosis (ARTS), we examined cross-sectionally the associations between ARTS, cortical thinning, and cognition.

View Article and Find Full Text PDF

Inhalation Exposure to Airborne Prothioconazole Caused by Unmanned Aerial Vehicles Application and Potential Lung Health Effects.

J Agric Food Chem

January 2025

Joint Research Center for Food Nutrition and Health of IHM, School of Plant Protection, Anhui Agricultural University, Hefei, Anhui 230036, China.

The use of unmanned aerial vehicle (UAV) has greatly improved pesticide effectiveness and control efficiency; however, the risk of inhalation exposure to pesticides caused by spray drift requires urgent attention. This study is the first to investigate residue distribution and inhalation exposure risk of airborne prothioconazole and its metabolite prothioconazole-desthio during UAV application. The maximum detected unit exposure of prothioconazole and prothioconazole-desthio in airborne particulate matter was 0.

View Article and Find Full Text PDF

Effects of Biceps Rerouting on In Vivo Glenohumeral Kinematics in the Treatment of Large-to-Massive Rotator Cuff Tears.

Am J Sports Med

January 2025

Department of Sports Medicine, Shanghai Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: Arthroscopic repair with the biceps rerouting (BR) technique has been determined to lead to promising clinical and biomechanical outcomes for treating large-to-massive rotator cuff tears (LMRCTs). However, the in vivo effects of BR on glenohumeral kinematics during functional shoulder movements have not been fully elucidated.

Purpose: To investigate whether BR provides a better restoration of shoulder kinematics compared with conventional rotator cuff repair (RCR).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!