Antibacterial Activity of L-Lysine-α-Oxidase from the Trichoderma.

Bull Exp Biol Med

T. T. Berezov Department of Biochemistry, Medical Faculty of the Medical Institute, the Peoples' Friendship University of Russia, Moscow, Russia.

Published: October 2017

We studied the effects of a concentrate of metabolites of Trichoderma harzianum Rifai F-180, an active producer of L-lysine-α-oxidase, and homogenous enzyme on a highly virulent bacteria Erwinia amylovora. The producer of antitumor and antiviral Trichoderma enzyme L-lysine-α-oxidase was cultured on a processing system of G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences (Pushchino). Activity of L-lysine-α-oxidase in the prepared concentrate of metabolic products of the producer was 5.4 U/ml, and activity of the homogenous enzyme was 50 U/ml. Antibacterial activity of the enzyme was shown in our experiments.

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http://dx.doi.org/10.1007/s10517-017-3901-0DOI Listing

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