This work focuses on the development of a sophisticated technique via STR typing to unequivocally verify the authenticity of urine samples before sent to laboratories. STR profiling was conducted with the CSF1PO, TPOX, TH01 Multiplex System coupled with a smartphone-based detection method. The promising capability of the method to identify distinct STR profiles from urine of different persons opens the possibility to conduct sample authenticity tests. On-site STR profiling could be realized with a self-contained autonomous device with an integrated PCR microchip shown hereby.
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http://dx.doi.org/10.1109/EMBC.2017.8037596 | DOI Listing |
BMC Cancer
January 2025
Department of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Background: Inadequate treatment responses, chemotherapy resistance, significant heterogeneity, and lengthy treatment durations create an urgent need for new pancreatic cancer therapies. This study aims to investigate the effectiveness of gemcitabine-loaded nanoparticles enclosed in an organo-metallic framework under ketogenic conditions in inhibiting the growth of MIA-PaCa-2 cells.
Methods: Gemcitabine was encapsulated in Metal-organic frameworks (MOFs) and its morphology and size distribution were examined using transmission electron microscopy (TEM) and Dynamic light scattering (DLS) with further characterization including FTIR analysis.
Food Chem
December 2024
International Joint Research Centre on Food Security, Pathum Thani 12120, Thailand; Institute for Global Food Security (IGFS), School of Biological Sciences, Queen's University Belfast (QUB), BT9 5DL, UK.
Essential oils (EOs) are gaining popularity due to their potent antibacterial properties, as well as their applications in food preservation and flavor enhancement, offering growth opportunities for the food industry. However, their widespread use as food preservatives is limited by authenticity challenges, primarily stemming from adulteration with cheaper oils. This study investigated a rapid, cost-effective, and non-destructive method for assessing the authenticity of widely used Mentha and Ocimum EOs.
View Article and Find Full Text PDFFood Chem
January 2025
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, PR China; Key Laboratory of Biology and Cultivation of Herb Medicine, Ministry of Agriculture and Rural Affairs, Beijing 100700, PR China. Electronic address:
Ensuring food traceability is essential for maintaining safety and authenticity. Angelica sinensis (Oliv.) Diels (AS), a medicinal food prized for its rich nutritional value and tonic effects, is frequently vulnerable to geographic origin fraud.
View Article and Find Full Text PDFFood Res Int
January 2025
New Hazardous Substances Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong, Cheongju, Chungcheongbuk-do 28159, Republic of Korea. Electronic address:
Honey is highly vulnerable to food fraud, and there are growing concerns about product authenticity. The commonly used stable carbon isotope ratios in the Calvin (C3) and Hatch-Slack (C4) photosynthesis cycles in plant feed cannot distinguish between beet-sugar-fed honey and natural honey. However, 3-methoxytyramine (3-MT) can be used as specific biomarker for identifying adulteration of beet-sugar-fed honey.
View Article and Find Full Text PDFJ Fluoresc
January 2025
College of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou, 450001, China.
A highly practical Schiff base fluorescent probe, (E)-3-amino-N'-((7-(diethylamino)-2-oxo-2 H-chromen-3-yl)methylene)thiophene-2-carbohydrazide (M), with a facile synthetic route has been successfully developed. M has been utilized for the specific detection of Cu in THF/HO Tris buffer solution (v/v = 9:1, 0.01 M, pH = 7.
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