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Regarding the "Renal dysfunction in AQP4 NMOSD and MS; a potential predictor of relapse and prognosis".
Clin Immunol
July 2024
Department of Clinical Laboratory, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi 341000, China. Electronic address:
Reduced serum IgG galactosylation is associated with increased inflammation during relapses of neuromyelitis optica spectrum disorders.
Front Immunol
April 2024
Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Background And Objective: Post-translational modifications of antibodies, with a specific focus on galactosylation, have garnered increasing attention in the context of understanding the pathogenesis and therapeutic implications of autoimmune diseases. However, the comprehensive scope and the clinical significance of antibody galactosylation in the context of Neuromyelitis Optica Spectrum Disorder (NMOSD) remain enigmatic.The primary aim of this research was to discern disparities in serum IgG galactosylation levels between individuals in the acute stage of NMOSD relapse and their age- and sex-matched healthy counterparts.
View Article and Find Full Text PDFIn patients with mild disability NMOSD: is the alteration in the cortical morphological or functional network topological properties more significant.
Front Immunol
February 2024
Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Objective: To assess the alteration of individual brain morphological and functional network topological properties and their clinical significance in patients with neuromyelitis optica spectrum disorder (NMOSD).
Materials And Methods: Eighteen patients with NMOSD and twenty-two healthy controls (HCs) were included. The clinical assessment of NMOSD patients involved evaluations of disability status, cognitive function, and fatigue impact.
Commentary: Targeting chemoattractant chemokine (C-C motif) ligand 2 derived from astrocytes is a promising therapeutic approach in the treatment of neuromyelitis optica spectrum disorders.
Front Immunol
November 2023
Center on Translational Neuroscience, College of Life & Environmental Science, Minzu University of China, Beijing, China.
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