Comparative study of 4D CTA and DSA for vascular assessment in moyamoya disease.

Purpose: To evaluate the vascular stenosis and collateral circulation in moyamoya disease using 4D CTA.

Methods: Two neuroradiologists evaluated 4D CTA and DSA for 101 moyamoya patients. The performance of 4D CTA relative to DSA was determined using consistency checks (kappa values, 95% CI) and correlation analysis.

Results: The kappa values were 0.714 (modified Suzuki score), 0.846 (Houkin score), 0.594 (basicranial moyamoya vessels), 0.435 (posterior circulation collaterals) and 0.591 (ECA collaterals). The correlation coefficients were 0.843, 0.872, 0.792, 0.635 and 0.797.

Conclusions: 4D CTA showed strong consistency and correlation with DSA in the vascular stenosis score, but was insufficient in collateral circulation evaluation.