Epithelial cells in tissues use their actin cytoskeletons to stick together, whereas unattached cells make active plasma membrane protrusions to migrate. In this issue, Wood et al. (2017. https://doi.org/10.1083/jcb.201612006) show that the junction component α-catenin is critical in freely moving cells to promote adhesion and migration.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674902 | PMC |
http://dx.doi.org/10.1083/jcb.201709056 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!