AI Article Synopsis
- Supraventricular ectopic complexes (SVEC) increase the risk of recurrent atrial fibrillation (AF), but their impact varies by age group, particularly in patients above and below 57 years old.
- A study with 260 patients examined the effects of antiarrhythmic medication (AAD) and catheter ablation (CA), revealing that older patients (over 57) had a significantly higher rate of AF recurrence after CA compared to younger patients.
- High SVEC burden within three months post-CA was linked to increased AF recurrence in older patients, whereas no age-related differences were seen in those treated with AAD.
Article Abstract
Introduction: Supraventricular ectopic complexes (SVEC) are known risk factors of recurrent atrial fibrillation (AF). However, the impact of SVEC in different age groups is unknown. We aimed to investigate the risk of AF recurrence with higher SVEC burden in patients ±57years, respectively, after treatment with antiarrhythmic medication (AAD) or catheter ablation (CA).
Methods: In total, 260 patients with LVEF >40% and age ≤70 years were randomized to AAD (N=132) or CA (N=128) as first-line treatment for paroxysmal AF. All patients underwent 7-day Holter monitoring at baseline, and after 3, 6, 12, 18 and 24months and were categorized according to median age ±57years. We used multivariate Cox regression analyses and we defined high SVEC burden at 3months of follow-up as the upper 75th percentile >195SVEC/day. AF recurrence was defined as AF ≥1min, AF-related cardioversion or hospitalization.
Results: Age >57years were significantly associated with higher AF recurrence rate after CA (58% vs 36%, p=0.02). After CA, we observed a higher SVEC burden during follow-up in patients >57years which was not observed in the younger age group treated with CA (p=0.006). High SVEC burden at 3months after CA was associated with AF recurrence in older patients but not in younger patients (>57years: HR 3.4 [1.4-7.9], p=0.005). We did not find any age-related differences after AAD.
Conclusion: We found that younger and older patients respond differently to CA and that SVEC burden was only associated with AF recurrence in older patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijcard.2017.09.208 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo.
Nat Commun
October 2023
Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in highly malaria-endemic regions. We estimated incidence and prevalence of PCR-confirmed non-falciparum and Plasmodium falciparum malaria infections within a longitudinal study conducted in Kinshasa, Democratic Republic of Congo (DRC) between 2015-2017. Children and adults were sampled at biannual household surveys and routine clinic visits.
View Article and Find Full Text PDFEpidemiology of and spp. in a highly malaria-endemic country: a longitudinal cohort study in Kinshasa Province, Democratic Republic of Congo.
medRxiv
April 2023
Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Article Synopsis
- Non-falciparum malaria species are increasingly recognized as significant contributors to malaria cases in sub-Saharan Africa, particularly in the Democratic Republic of Congo (DRC), which has a high incidence of malaria.
- A longitudinal study in Kinshasa Province (2015-2017) found that the incidence of non-falciparum species was 11% for Plasmodium vivax and 7% for Plasmodium ovale within one year, while the incidence for Plasmodium falciparum was significantly higher at 67%.
- Non-falciparum infections were more common in rural areas and among school-age children, and while there were some associations with anemia, they weren't consistent, indicating that
A long wait: barriers to discharge for long length of stay patients.
Postgrad Med J
October 2018
Department of Medicine, Stanford University, Stanford, California, USA.
Introduction: Reducing long length of stay (LLOS, or inpatient stays lasting over 30 days) is an important way for hospitals to improve cost efficiency, bed availability and health outcomes. Discharge delays can cost hundreds to thousands of dollars per patient, and LLOS represents a burden on bed availability for other potential patients. However, most research studies investigating discharge barriers are not LLOS-specific.
View Article and Find Full Text PDFDescription and Comparative Genomics of subsp. subsp. nov., sp. nov., sp. nov., and sp. nov., Novel Macrococci From Human Clinical Material With Virulence Potential and Suspected Uptake of Foreign DNA by Natural Transformation.
Front Microbiol
June 2018
Division of Genetics and Molecular Biology, Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czechia.
The genus is a close relative of the genus . Whilst staphylococci are widespread as human pathogens, macrococci have not yet been reported from human clinical specimens. Here we investigated Gram-positive and catalase-positive cocci recovered from human clinical material and identified as sp.
View Article and Find Full Text PDFThe impact of supraventricular ectopic complexes in different age groups and risk of recurrent atrial fibrillation after antiarrhythmic medication or catheter ablation.
Int J Cardiol
January 2018
Rigshospitalet, Copenhagen, Denmark.
Article Synopsis
- Supraventricular ectopic complexes (SVEC) increase the risk of recurrent atrial fibrillation (AF), but their impact varies by age group, particularly in patients above and below 57 years old.
- A study with 260 patients examined the effects of antiarrhythmic medication (AAD) and catheter ablation (CA), revealing that older patients (over 57) had a significantly higher rate of AF recurrence after CA compared to younger patients.
- High SVEC burden within three months post-CA was linked to increased AF recurrence in older patients, whereas no age-related differences were seen in those treated with AAD.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!