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http://dx.doi.org/10.1001/jama.2017.13861 | DOI Listing |
Cancers (Basel)
December 2024
Soft-Tissue, Peritoneum and Melanoma Surgical Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
Diagnosis of nevoid melanoma (NeM) is often difficult because NeM closely resembles a common nevus clinically and histologically. A retrospective study was conducted on 110 patients diagnosed with and/or treated for primary nevoid melanoma at the Veneto Institute of Oncology and at the University Hospital of Padua from August 1999. Mean Breslow thickness was of 1.
View Article and Find Full Text PDFMymensingh Med J
January 2025
Dr Md Mostaque Mahmud, Associate Professor, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:
Flegel's disease (FD) or hyperkeratosis lenticularis perstans (HLP) is an extremely exceptional skin disease typified by hyper-keratotic papules usually found on the lower extremities. Only the histopathological study is the confirmatory test for diagnosis this disease. The treatment of Flegel's disease is not yet settled as a standard one.
View Article and Find Full Text PDFBMJ Case Rep
December 2024
Pharmacy Practice, JSS College of Pharmacy, Mysuru, Karnataka, India
Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition associated with the sudden onset of high-grade fever, painful rashes usually on the upper body, leukocytosis and neutrophilia. Approximately 21% of patients with Sweet syndrome have a concurrent malignancy, 80% of which are linked to haematological diseases, especially myelodysplastic syndrome and acute myeloid leukaemia. This is a case report of a woman in her 50s who was recently diagnosed with acute myeloid leukaemia and was started on decitabine 20 mg/m (40 mg).
View Article and Find Full Text PDFJPRAS Open
March 2025
Department of Biology, Universidad del Cauca, Popayán, Colombia.
The impact of breast implants on the immune system has been debated since their introduction in the 1960s, linking silicone to systemic autoimmune diseases. Recent studies have shown that silicone gel can migrate from the implant capsule, triggering immune responses by proliferating immune cells and releasing cytokines, affecting T-cell function. Silicone particles can induce the release of IL-1β and activate the NALP3 inflammasome and B cells, causing an imbalance in regulatory T cells, responder T cells, and Th17 cells.
View Article and Find Full Text PDFCutis
October 2024
Drs. Satasia and Hamadani are from the Department of Internal Medicine, Saint Peter's University Hospital, New Brunswick, New Jersey. Dr. Fein is from the Department of Oncology, Robert Wood Johnson University Hospital, New Brunswick.
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