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A mechanosensitive Ca channel activity is dependent on the developmental regulator DEK1. | LitMetric

A mechanosensitive Ca channel activity is dependent on the developmental regulator DEK1.

Nat Commun

Laboratoire Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCB Lyon 1, CNRS, INRA, F-69342, Lyon, France.

Published: October 2017

AI Article Synopsis

  • Cells respond to mechanical stress, which is important for growth and development in both animals and plants.
  • The PIEZO1 channel in animals influences cell division and development, particularly in the vascular system.
  • Research shows that the DEK1 protein in Arabidopsis plants is linked to a mechanically activated calcium current, indicating that mechanical stress perception is crucial for plant development.

Article Abstract

Responses of cells to mechanical stress are thought to be critical in coordinating growth and development. Consistent with this idea, mechanically activated channels play important roles in animal development. For example, the PIEZO1 channel controls cell division and epithelial-layer integrity and is necessary for vascular development in mammals. In plants, the actual contribution of mechanoperception to development remains questionable because very few putative mechanosensors have been identified and the phenotypes of the corresponding mutants are rather mild. Here, we show that the Arabidopsis Defective Kernel 1 (DEK1) protein, which is essential for development beyond early embryogenesis, is associated with a mechanically activated Ca current in planta, suggesting that perception of mechanical stress plays a critical role in plant development.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647327PMC
http://dx.doi.org/10.1038/s41467-017-00878-wDOI Listing

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