Japan has become a "super-aged" society, in which more than 20% of the population is over the age of 65 years. As the incidence rates of both dementia and epilepsy are high in elderly individuals, the prevalence rates of dementia and epilepsy have both increased in recent years. Dementia and epilepsy are often characterized by ambiguous symptoms, with numerous concomitant symptoms observed in these patients. Moreover, many reports indicate that the forgetfulness observed in dementia patients was actually due to the occurrence of epileptic seizures. Because Japan is currently a super-aged society, it is important to understand the characteristics of and relationships between dementia and epilepsy.
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http://dx.doi.org/10.11477/mf.1416200880 | DOI Listing |
J Alzheimers Dis
January 2025
Division of Neurosurgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taipei.
Although the association between dementia such as Alzheimer's disease and traumatic brain injury (TBI) is well established, there are significant knowledge gaps with respect to the perspective of dementia and epilepsy without TBI. We aimed to investigate the relationship between dementia and epilepsy in a population-based study of patients without history of TBI. This study included a random sample of 30,715 patients with no history of TBI, including 6143 with epilepsy as the study cohort and 24,572 without epilepsy as the comparison cohort.
View Article and Find Full Text PDFEpilepsy Res
January 2025
Department of Neurology, The Affiliated Hospital of Yangzhou University, Yangzhou University, No. 368, Hanjiang Road, Yangzhou, Jiangsu 225012, China. Electronic address:
Purpose: Epilepsy is a widespread neurological disorder that increases the risk of cognitive impairment (CI) or dementia. We aimed to assess the relationship between cognition and interictal electroencephalogram (EEG) in epilepsy patients, using the Grand Total EEG (GTE) score. Additionally, we investigated the GTE score's utility in the early detection of CI in these patients.
View Article and Find Full Text PDFBrain Inj
January 2025
Department of Biomedical Science and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, USA.
Background: Chronic neurologic deficits from traumatic brain injury (TBI) and subsequent infectious encephalitis are poorly characterized.
Methods: Using TriNetX database we queried patients 18 years or older with a confirmed diagnosis of encephalitis between 2016 and 2024. Patient cohorts included those with a diagnosis of TBI at least one month before encephalitis ( = 1,038), those with a diagnosis of a TBI anytime before encephalitis ( = 1,886), and those with encephalitis but no TBI, ( = 45,210; = 45,215).
Nat Rev Neurol
January 2025
Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, UK.
Evidence suggests that anthropogenic climate change is accelerating and is affecting human health globally. Despite urgent calls to address health effects in the context of the additional challenges of environmental degradation, biodiversity loss and ageing populations, the effects of climate change on specific health conditions are still poorly understood. Neurological diseases contribute substantially to the global burden of disease, and the possible direct and indirect consequences of climate change for people with these conditions are a cause for concern.
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