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| http://dx.doi.org/10.2215/CJN.09810917 | DOI Listing |
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Granulomas, organized aggregates of immune cells which form in response to (), are characteristic but not exclusive of tuberculosis (TB). Despite existing investigations on TB granulomas, the determinants that differentiate host-protective granulomas from granulomas that contribute to TB pathogenesis are often disputed. Thus, the goal of this narrative review is to help clarify the existing literature on such determinants.
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Article Synopsis
- The study investigated the safety of high-moderate and low-moderate systemic hypothermia during circulatory arrest in patients with acute DeBakey I aortic dissection, focusing on spinal cord protection.
- Over 1,700 patients were analyzed, showing that those in the nonmalperfusion subgroup experienced lower in-hospital mortality and kidney injury rates with high-moderate hypothermia compared to low-moderate hypothermia.
- In contrast, patients with preoperative malperfusion had a higher risk of developing paraplegia with high-moderate hypothermia, suggesting that low-moderate hypothermia may be safer for this subgroup.
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