Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for emergency cardiac support.

J Crit Care

Faculty of Medicine, University of British Columbia, 317-2194 Health Sciences Mall, V6T 1Z3 Vancouver, British Columbia, Canada; Department of Medicine, Division of Critical Care, Faculty of Medicine, University of British Columbia, Critical Care, Vancouver General Hospital, 2438-855 West 12th Avenue, V5Z 1M9 Vancouver, British Columbia, Canada.

Published: April 2018

Purpose: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may provide benefit to patients in refractory cardiac arrest and cardiogenic shock. We aim to summarize our center's 6-year experience with resuscitative VA-ECMO.

Materials And Methods: A retrospective medical record review (April 2009 to 2015) was performed on consecutive non-cardiotomy patients who were managed with VA-ECMO due to refractory in- or out-of-hospital cardiac (IHCA/OHCA) arrest (E-CPR) or refractory cardiogenic shock (E-CS) with or without preceding cardiac arrest. Our primary outcome was survival to hospital discharge and good neurological status (Cerebral Performance Category 1-2).

Results: There were a total of 22 patients who met inclusion criteria of whom 9 received E-CPR (8 IHCA, 1 OHCA) and 13 received E-CS. The median age for E-CPR patients was 52 [IQR 45, 58] years, and 54 [IQR 38, 64] years for E-CS patients. Cardiac arrest duration was 70.33 (SD 39.56) min for the E-CPR patients, and 24.67 (SD 26.73) min for the 9 patients treated with E-CS who had previously arrested. Initial cardiac arrest rhythms were pulseless electrical activity (39%), ventricular fibrillation (33%), or ventricular tachycardia (28%). A total of 18/22 patients were successfully weaned from VA-ECMO (78%); 16 patients survived to hospital discharge (73%) with 15 in good neurological condition.

Conclusion: The initiation of VA-ECMO at our center for treatment of refractory cardiac arrest and cardiogenic shock yielded a high proportion of survivors and favorable neurological outcomes.

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Source
http://dx.doi.org/10.1016/j.jcrc.2017.10.011DOI Listing

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