AI Article Synopsis
- The study aimed to compare cyclophilin A levels in mothers and cord blood of women with severe preeclampsia to those with normal pregnancies and examine any correlation with vitamin D and zinc levels.
- Thirty-nine pregnant women were studied, with results indicating that those with severe preeclampsia had significantly higher cyclophilin A levels than those with normal pregnancies.
- Despite the elevated cyclophilin A levels, the research found no significant correlations between cyclophilin A and either zinc or vitamin D levels.
Article Abstract
Objective: To investigate maternal and cord blood cyclophilin A level in severe preeclampsia compared with normal pregnancy and its correlation with vitamin D and zinc level.
Methods: We conducted a cross-sectional observational study of pregnant women who gave birth in Cipto Mangunkusumo Hospital between January and April 2014.
Results: Thirty-nine subjects were included. Subjects with severe preeclampsia have higher serum cyclophilin A levels compared with normotensive pregnancy (1299.60 vs. 1039.50; p 0.017). Maternal cyclophilin A, vitamin D, and zinc correlation were not statistically significant (p 0.189 & p 0.853).
Conclusion: Cyclophilin A levels in severe preeclampsia is higher compared to normal pregnancy. There is no correlation between cyclophilin A, zinc, and vitamin D.
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| http://dx.doi.org/10.1080/10641955.2017.1385792 | DOI Listing |
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