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The effect of phlebotomy and placement of an intravenous catheter on plasma catecholamine and serum copeptin concentrations.
J Pediatr Endocrinol Metab
December 2024
Division of Pediatric Endocrinology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Objectives: Limited data are available on the hormonal response of children to venepuncture or intravenous cannulation (IVC). Catecholamines [epinephrine (E) and norepinephrine (NE)] have been traditionally recognized as stress hormones. Copeptin, the carboxyl-terminus of the arginine vasopressin (AVP) precursor peptide, is also a known marker for stressful stimuli, including myocardial infarction, critical illness, and sepsis.
View Article and Find Full Text PDFThe effects of controlled acute psychological stress on serum cortisol and plasma metanephrine concentrations in healthy subjects.
Ann Clin Biochem
November 2024
Centre for Medical Education, Queen's University Belfast, Belfast, UK.
Background: As cortisol and metanephrine are involved in the stress response, it is often recommended that individuals are relaxed at the time of venepuncture, however, evidence behind these recommendations is lacking. We investigated the effects of acute psychological stress on serum cortisol and plasma metanephrine concentrations in healthy individuals exposed to varying levels of psychological stress and compared these results to self-reported measures of stress.
Methods: Ten medical students completed two medical in-person simulations (one low-complexity, one high-complexity) in a random order.
Effects of clowning on anxiety, stress, pain, and hormonal markers in paediatric patients.
BMC Pediatr
November 2024
Faculty of Health Sciences, Universidad Tecnológica de Pereira, Carrera 27 10-02 Barrio Álamos, Pereira, 660003, Colombia.
Background: Clowning has been used in many hospitals, particularly for children. Studies suggest the effectiveness of this methodology, but more evidence is needed. The aim of this study was to evaluate the impact of a humour therapy intervention on biological markers, pain and anxiety levels in paediatric patients.
View Article and Find Full Text PDFFeline blood donation: Description and adverse reactions from 29 201 donation events between 2019 and 2023.
J Vet Intern Med
November 2024
Animal Blood Bank, Porto, Portugal.
Article Synopsis
- Feline blood transfusions are crucial for treating illnesses in cats, but ensuring the safety of donor cats is essential, as they can experience adverse reactions during the process.
- A study analyzed 29,201 donation events from 7812 cats over five years, focusing on the frequency and types of adverse reactions, the use of sedation, and identifying risk factors.
- The findings revealed a low rate of adverse reactions (0.29%), primarily cardiorespiratory and behavioral, with conscious donation being a significant risk factor; it suggested using sedation and improving caregiver education to minimize these reactions.
Intravenous fluid therapy compared to no treatment following blood donation in cats: a randomised controlled trial.
J Small Anim Pract
September 2024
Department of Clinical Science and Services, Queen Mother Hospital for Animals, Royal Veterinary College, Hatfield, UK.
Objectives: There is currently no consensus regarding the use of intravenous fluid therapy in feline patients post-blood donation in veterinary medicine. The primary aim of this study was to determine whether blood donation can be performed safely without post-donation intravenous fluid therapy. The secondary aim was to report owner-noted post-donation changes.
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