18F-FAZA PET/CT Hypoxia Imaging of High-Grade Glioma Before and After Radiotherapy.

Clin Nucl Med

From the *Nuclear Medicine Department, IRCCS San Raffaele Scientific Institute; †Radiotherapy Department, San Raffaele Scientific Institute; and ‡Neuroradiology Unit and CERMAC, San Raffaele Scientific Institute and Vita-Salute San Raffaele, Milan, Italy.

Published: December 2017

A 57 year-old man underwent MRI with dynamic susceptibility contrast and dynamic contrast-enhanced perfusion for neurological symptoms suggesting the diagnosis of high-grade glioma. A F-FAZA PET/CT was performed because of the enrollment in a prospective clinical trial. Subsequent radiotherapy treatment has been planned based on conventional imaging; moreover, a F-FAZA PET/CT-guided treatment planning highlighting hypoxic regions has been simulated. After radiotherapy treatment, the man underwent MRI and F-FAZA PET/CT, showing partial response.

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Source
http://dx.doi.org/10.1097/RLU.0000000000001850DOI Listing

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