Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Platelet-rich plasma effects on in vitro cells derived from pediatric patients with andrological diseases.
Sci Rep
December 2024
Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona, Verona, Italy.
Undescended testis and testicular torsion represent two frequent andrological diseases that affect the pediatric age. Despite these testicular disorders having different causes, they both negatively influence fertility in adulthood mainly due to the accumulation of reactive oxygen species (ROS), which represents the primary molecular damage underlying their long-term effects. The gold standard of treatment for both pathologies is surgery; however, it cannot guarantee an optimal fertility outcome in all clinical cases, underscoring the need to identify effective adjuvant therapies that may target the augmented ROS levels.
View Article and Find Full Text PDFMicrodissection testicular sperm extraction outcomes in azoospermic patients post-orchidopexy surgery: A systematic review and meta-analysis.
PLoS One
November 2024
Department of Andrology and Sexual Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Cryptorchidism is a common cause of male infertility, often necessitating microdissection testicular sperm extraction (m-TESE) for sperm retrieval post-surgery. However, uncertainties persist regarding m-TESE outcomes and influencing factors following cryptorchidism surgery. A systematic review and meta-analysis were conducted to evaluate sperm retrieval rates (SRR) among patients undergoing m-TESE after cryptorchidism surgery.
View Article and Find Full Text PDFPure intertubular seminoma (PITS) of the testis: A multi-institutional cohort of a rare growth pattern of seminoma.
Hum Pathol
November 2024
Department of Pathology and Laboratory Medicine, CORE Diagnostics, India. Electronic address:
Article Synopsis
- Pure intertubular seminoma (PITS) is a rare type of testicular cancer where seminoma cells are found in testicular interstitium without forming a noticeable mass or diffuse growth, leading to challenges in diagnosis.
- This condition often goes unnoticed and is usually diagnosed incidentally during evaluations for testicular pain, infertility, or other issues, with only a minority of cases presenting with metastasis.
- A study involving 15 patients revealed that the average age at presentation was 29, and common symptoms included undescended testis, testicular pain, and infertility, while most patients had normal serum markers and no visible tumors at the time of diagnosis.
Decoding the pathogenesis of spermatogenic failure in cryptorchidism through single-cell transcriptomic profiling.
Cell Rep Med
September 2024
State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China; Department of Urology, Peking University Third Hospital, Beijing, China. Electronic address:
Cryptorchidism, commonly known as undescended testis, affects 1%-9% of male newborns, posing infertility and testis tumor risks. Despite its prevalence, the detailed pathophysiology underlying male infertility within cryptorchidism remains unclear. Here, we profile and analyze 46,644 single-cell transcriptomes from individual testicular cells obtained from adult males diagnosed with cryptorchidism and healthy controls.
View Article and Find Full Text PDFImaging Aspects in a Case of Persistent Müllerian Duct Syndrome (PMDS): A Case Report and Overview.
Cureus
July 2024
Department of Urology, Clinical Hospital "Prof. Dr. Theodor Burghele", Bucharest, ROU.
Persistent Müllerian duct syndrome (PMDS) is a rare kind of internal male pseudohermaphroditism. The patient, who has a male karyotype and phenotypic characteristics, exhibits Müllerian duct derivatives such as the uterus, cervix, fallopian tubes, and upper two-thirds of the vagina. This article provides a comprehensive analysis of the CT and MRI characteristics of a case of PMDS in a 35-year-old male patient who sought medical attention at our clinic due to pain in the left inguinal region and the presence of undescended testes on both sides.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!