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http://dx.doi.org/10.3904/kjim.2014.254 | DOI Listing |
JACC Case Rep
January 2025
National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
A 35-year-old man presented to the emergency department with reports of chest pain, progressive shortness of breath, and pedal edema. He had a history of multiple hospital admissions without improvement. Multimodality imaging revealed a suspected giant right atrial myxoma.
View Article and Find Full Text PDFInt J Surg Pathol
January 2025
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Giant cell tumors are neoplasms that usually occur in the long bones of young adults. They can rarely present in the soft tissue and may display malignant behavior. Giant cell malignancies have previously been reported as tumors primary of the uterus but are exceptionally rare.
View Article and Find Full Text PDFPheochromocytoma (PHEO) currently is considered to be malignant due to metastatic potential. One of the most common familial forms of PHEO is multiple endocrine neoplasia syndrome (MEN) type 2. The penetrance of PHEO in MEN2 syndrome is up to 50% of cases.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Pathology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hosipital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China.
In this article, we report the first case of a 61-year-old woman who was diagnosed with both nodules and cystic lesions in her lungs. The lung nodules were diagnosed as ALK-positive histiocytosis (APH) carrying an gene fusion, which microscopically displayed a mixed morphology of foamy cells, spindle cells, and Touton's giant cells. Immunohistochemistry showed expression of CD163, CD68, and ALK, while fluorescence hybridization (FISH) with second-generation sequencing (NGS) showed the ALK gene fusion with the FLCN gene variant.
View Article and Find Full Text PDFComput Biol Med
January 2025
Department of Pathology, Peking University Health Science Center, 38 College Road, Haidian, Beijing, 100191, China; Department of Pathology, School of Basic Medical Sciences, Third Hospital, Peking University Health Science Center, Beijing, 100191, China. Electronic address:
Background: Ovarian cancer is among the most lethal gynecologic malignancy that threatens women's lives. Pathological diagnosis is a key tool for early detection and diagnosis of ovarian cancer, guiding treatment strategies. The evaluation of various ovarian cancer-related cells, based on morphological and immunohistochemical pathology images, is deemed an important step.
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