In this study, we develop an in vivo dielectric imaging technique that measures capacitance using pin-type electrode arrays. Compared to normal tissues, cancer tissues exhibit higher capacitance values, allowing us to image the cancer region and monitor the chemotherapeutic effects of cancer in real-time. A comparison with the histopathological results shows that the in vivo dielectric imaging technique is able to detect small tumors (<3 mm) and tumor-associated changes. In addition, we demonstrate that cancer and inflammation may be distinguished by measuring the capacitance images at different frequencies. In contrast, the positron emission tomography using 2-[F]-fluoro-2-deoxy-D-glucose was not capable of discriminating between cancer and inflammation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640678 | PMC |
| http://dx.doi.org/10.1038/s41598-017-13545-3 | DOI Listing |
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