Chemical Constitute and Larvicidal Activity of Fractions of Plant against Malaria Vector .

J Arthropod Borne Dis

Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Published: March 2017

Backgrand: The genus , belongs to Lamiaceae family, is one of the exclusive subspecies in the flora of Iran. The plants of this genus are used traditionally for treatment of joints pain, gout, jaundice, and as insecticide.

Methods: larvicidal activity of methanol 80% extract and partition fractions of hexane, chloroform, and ethyl acetate obtained from aerial parts of subspecies against malaria vector was evaluated. Phytochemical study of active fraction was analyzed using column chromatography and spectroscopy.

Results: According to the results, among different fractions, hexane fraction has the most larvicidal activity with mortality rate of 100% in concentration of 102 ppm and LC of 95.66ppm. The structure of compound 1, main phytoecdysteroid compound separated from hexane fraction, was determined to be ajugalide-E.

Conclusion: The results suggested that the hexane fraction of subsp could be used as a natural and biodegradable insecticide.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629293PMC

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