High-dose intravenous thyroxine (T4) is the preferable treatment for myxedema coma. We describe the clinical course of a 69-year-old man who presented with myxedema coma and received oral levothyroxine (LT4) therapy (1 mg) in a split dose. This suggests split high-dose oral LT4 as a therapeutic option in myxedema coma.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628197PMC
http://dx.doi.org/10.1002/ccr3.1131DOI Listing

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