AI Article Synopsis
- Non-invasive prenatal testing (NIPT) for detecting fetal trisomies can sometimes reveal the presence of maternal cancer.
- This study presents another case where maternal cancer was identified during routine NIPT, suggesting that extensive abnormalities are generally not due to fetal conditions.
- Patients should be informed about the possibility of incidental findings and given the option to opt out of receiving results not related to trisomy, with international guidelines recommended for better patient counseling.
Article Abstract
What is already known about this subject? Non invasive prenatal testing for fetal trisomies 13, 18, and 21 occasionally identifies maternal cancer. What does this study add? A further case of maternal cancer incidentally diagnosed by routine NIPT. Extensive NIPT abnormalities are unlikely to be of fetal origin. Information given to patients should also adequately advise patients on potential incidental findings and might offer the option to opt out of receiving results beyond the trisomy report. International guidelines would improve patient counseling.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767741 | PMC |
| http://dx.doi.org/10.1002/pd.5168 | DOI Listing |
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