Objective: The aim of the study was to evaluate alcohol consumption in a representative sample of the population of the city of Brno, as part of research on cardiovascular risk factors.
Methods: Cross-sectional survey on a sample of 2,160 randomly selected residents 35-65 years old was carried out. For the invited volunteers who became a part of the investigation, alcohol consumption was determined in a controlled, face to face interview structured in accordance with a special questionnaire form. The frequency of alcohol consumption during the previous year was determined, in more detail during the last month (including quantification using "units of alcohol", their normal and maximum level of drinking, and any association between alcohol consumption and meals), and during the last week in the form of a complete, beverage specified and quantified 7-day recall period. Typical patterns of alcohol consumption were explored by the means of cluster analysis.
Results: During the past 12 months, 90.0% of the men and 79.0% of the women had consumed alcohol, the rest can be considered abstinent. The most commonly reported frequency was 2-4 times per week (35.6% of the men), or 1-3 times per month (22.8% of the women). Daily or almost daily consumption was reported by 24.8% of the men and 12.8% of the women. The number of units of alcohol consumed usually on one occasion amounts to an average of 3.88±4.80 for the men and 2.25±1.39 for the women, but the amount most often cited by both sexes was 2 drinks (36.4% of the men and 40.4% of the women). The largest amount consumed on any occasion during the last 30 days was 5 or more units in 69.3% of the men, and in 33.9% of the women it was 4 or more units (this amount of alcohol leads to a blood alcohol concentration (BAC) of 0.08, the border of drunkenness). In 19.9% of the men and 7.5% of the women, this border was exceeded more than 5 times in the past month. Only 14.7% of the men and 10.3% of the women reported that the majority of their alcohol consumption occurs with food; on the contrary, 64.3% of the men and 77.6% of the women drinkers drink it either always without food or only rarely with it. During the past week, 81.6% of the men and 63.4% of the women drank alcohol (p<0.001, chi-square). The average value of consumption for one man was 11.57±11.91 doses, and for one woman 4.68±6.38 doses per week (p<0.001, t-test). A total of 17.8% of the men exceeded the limit of 21 doses per week, and 7.4% of the women exceeded 14 doses/week. After converting the weekly consumption into the number of units of alcohol per week expressed in litres per year, the total average consumption was 5.01±6.36 litres; for the men 7.26±7.62 litres and for the women 3.02±4.08 litres of pure alcohol per person annually. Consumption during the week was not uniform (p<0.001, ANOVA), with the highest occurring on Saturday, followed by Friday. The men mostly drank beer (62.9% of the total volume of alcohol), the women wine (68.6%). The cluster analysis identified 5 clusters of respondents, based on a set of alcohol consumption variables, as follows: very heavy drinking (1.6% of the respondents who drink alcohol); heavy drinking (8.8%); binge drinking (6.3%); moderate drinking (31.1%); and occasional drinking (52.3%).
Conclusions: The results show a relatively high consumption of alcohol in the examined group. The recommended weekly limits were exceeded by only a small portion, but that consumption had a binge character. Conversion into a form allowing comparison with conventional national statistics shows a significantly lower consumption than these reported statements. Overall, men consume significantly more alcohol than women.
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http://dx.doi.org/10.21101/cejph.a4481 | DOI Listing |
Addiction
January 2025
Alcohol Research Group, Public Health Institute, Emeryville, CA, USA.
Aim: We applied the Institute of Medicine (IOM) definition of racial and ethnic disparities in healthcare to estimate disparities in alcohol-related problems. This estimation involved adjusting for drinking patterns, gender and age, with observed disparities further explained by socioeconomic status (SES). We compared results of five statistical approaches which use different methods for adjusting covariates.
View Article and Find Full Text PDFBMC Med
January 2025
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Background: Since older adults spend significant time in their neighborhood environment, environmental factors such as neighborhood socioeconomic disadvantage, high racial segregation, low healthy food availability, low access to recreation, and minimal social engagement may have adverse effects on cognitive function and increase susceptibility to dementia. DNA methylation, which is associated with neighborhood characteristics as well as cognitive function and white matter hyperintensity (WMH), may act as a mediator between neighborhood characteristics and neurocognitive outcomes.
Methods: In this study, we examined whether DNA methylation in peripheral blood leukocytes mediates the relationship between neighborhood characteristics and cognitive function (N = 542) or WMH (N = 466) in older African American (AA) participants without preliminary evidence of dementia from the Genetic Epidemiology Network of Arteriopathy (GENOA).
J Prev Alzheimers Dis
January 2025
School of Psychology, University of New South Wales, Sydney, NSW 2057, Australia; Neuroscience Research Australia, Margarete Ainsworth Building, 139 Barker St, Randwick NSW 2031, Australia. Electronic address:
Background: A brain healthy lifestyle, consisting of good cardiometabolic health and being cognitively and socially active in midlife, is associated with a lower risk of cognitive decline years later. However, it is unclear whether lifestyle changes over time also affect the risk for mild cognitive impairment (MCI)/dementia, and rate of cognitive decline.
Objectives: To investigate if lifestyle changes over time are associated with incident MCI/dementia risk and rate of cognitive decline.
Clin Gastroenterol Hepatol
January 2025
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:
Hepatocellular carcinoma (HCC) is a major concern for public health. Fatty liver disease, related to alcohol misuse or metabolic syndrome, has become the leading cause of chronic liver disease and HCC. The strong association between type 2 diabetes mellitus and HCC can be partly attributed to the development of metabolic dysfunction associated steatotic liver disease (MASLD).
View Article and Find Full Text PDFJ Clin Epidemiol
January 2025
Department of Health, Medicine and Caring Sciences, Linköping University, Sweden.
Objective: The term 'research participation effects' (RPEs) is intended to capture features and artefacts of study design that may affect measured outcomes in ways that introduce bias into research findings, impacting inference and outcome validity. This systematic review aims to identify which RPEs have been studied in the context of alcohol research and provide an overview of estimates of RPEs on self-reported alcohol consumption.
Study Design And Setting: This systematic review summarises the available evidence on research participation effects in alcohol research.
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