Three new isoflavones, 7-acetyl-4',6-dimethoxy-isoflavone (), 7-acetyl-4'-hydroxy-6-methoxy-isoflavone () and 7-acetyl-6,8-dimethoxy-4'-hydroxy-isoflavone (), together with five known flavones (-), were isolated from the (Willd.). Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compounds - were evaluated for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds and exhibited high anti-TMV activities with inhibition rates of 36.8 and 33.6%, respectively. The inhibition rates are higher than that of positive control. The other compounds also showed potential anti-TMV activities with inhibition rates in the range of 21.8~28.4%, respectively. The cytotoxicities of compounds - against five human tumour cell lines (NB4, A549, SHSY5Y, PC3 and MCF7) were also tested. The results revealed that compounds - showed weak inhibitory activities against some tested human tumour cell lines with IC values in the range of 1.2-3.6 μM.
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