Purpose: To describe a case of unilateral Vogt-Koyanagi-Harada (VKH) disease and associated multimodal imaging.
Methods: Retrospective case report.
Results: A 50-year-old Hispanic male presented with three days of painless decreased vision in his left eye, headache, and decreased hearing. His visual acuity was 20/20 in the right eye and counting fingers in the left eye. Examination of his right eye was unremarkable. Funduscopic examination of his left eye revealed multiple serous retinal detachments. Fluorescein angiography demonstrated late multifocal pinpoint hyperfluorescence in his left eye and a diagnosis of VKH disease was made. He was treated with oral prednisone. Serial re-examination demonstrated resolution of the serous retinal detachments and a taper of his oral prednisone was initiated with improvement of his visual acuity to 20/25.
Conclusions: Our patient had imaging and a clinical course that was consistent with VKH disease. This unilateral presentation may represent a clinical variant of VKH disease.
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http://dx.doi.org/10.1080/09273948.2017.1353638 | DOI Listing |
Ocul Immunol Inflamm
January 2025
Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.
Purpose: This study aimed to investigate demographic features, diagnoses of uveitis (intraocular inflammation), and real-world clinical practice in the use of local and systemic therapies for patients with uveitis in Tokyo, Japan.
Methods: Clinical records of 1,174 consecutive new patients (480 males, 694 females) referred to the Kyorin Eye Center, Kyorin University Hospital between January 2011 and December 2018 were retrospectively reviewed.
Results: Mean age at presentation was 52.
Antioxidants (Basel)
December 2024
College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Ferroptosis is an iron-dependent form of cell death, which is characterized by the uncontrolled and overwhelming peroxidation of cell membrane lipids. Ferroptosis has been implicated in the progression of various pathologies, including steatotic liver, heart failure, neurodegenerative diseases, and diabetes. Targeted inhibition of ferroptosis provides a promising strategy to treat ferroptosis-related diseases.
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December 2024
Department of Ophthalmology, Hanoi Medical University, Hanoi, Vietnam.
Purpose: To characterize the spectrum of uveitis in patients visiting three tertiary hospitals in Hanoi, Vietnam.
Methods: This study collected prospective and multicenter data from patients diagnosed with uveitis at three tertiary hospitals in Hanoi City, Vietnam, between January 2022 and January 2024. Data on age, sex, clinical and laboratory findings, and etiology were collected.
Front Med (Lausanne)
November 2024
Department of Ophthalmology, Beijing Tongren Hospital, Beijing, China.
Acute retinal necrosis (ARN) is a serious, sight-threatening condition characterized by rapidly progressive necrotizing retinitis, most commonly caused by varicella-zoster virus and herpes simplex virus. We report an atypical case of ARN in a 57-year-old immunocompetent male, initially misdiagnosed as Vogt-Koyanagi-Harada (VKH) disease. This case highlights the challenges in the early differential diagnosis of infectious and non-infectious uveitis.
View Article and Find Full Text PDFOcul Immunol Inflamm
December 2024
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
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