AI Article Synopsis
- A 78-year-old woman developed acute retinal necrosis after receiving the live zoster vaccine, which uses the Oka strain.
- Whole genome sequencing showed that the strain responsible for her condition was indeed the vaccine strain, confirming a direct link.
- The analysis revealed no new mutations or genetic changes that would indicate interaction with the wild-type Varicella zoster virus.
Article Abstract
We report acute retinal necrosis caused by the vaccine Oka strain following immunization of a 78-year-old woman with live zoster vaccine. Whole genome sequencing confirmed the ocular vOka strain to be derived from the vaccine and excluded the presence of new mutations or recombination with wild-type Varicella zoster virus.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849943 | PMC |
| http://dx.doi.org/10.1093/cid/cix683 | DOI Listing |
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