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Lockdown influence on diet and physical activity of seniors; has it weight consequences?
Cent Eur J Public Health
December 2024
Department of Radiology, AGEL Hospital, Levoca, Slovak Republic.
Objectives: Many studies draw attention to the negative consequences of the pandemic or lockdown on the well-being and lifestyle of different sections of the population. This study considers whether changes occurred in dietary regime and level of physical activity during three periods - before the pandemic, during the lockdown, and during the present in older Slovak adults. We also investigate whether individual weights changed during the pandemic.
View Article and Find Full Text PDFIntracellular concentration of ADA2 is a marker for monocyte differentiation and activation.
Front Med
January 2025
International Center for Aging and Cancer (ICAC), Hainan Medical University, Haikou, 571199, China.
Adenosine, a critical molecule regulating cellular function both inside and outside cells, is controlled by two human adenosine deaminases: ADA1 and ADA2. While ADA1 primarily resides in the cytoplasm, ADA2 can be transported to lysosomes within cells or secreted outside the cell. Patients with ADA2 deficiency (DADA2) often suffer from systemic vasculitis due to elevated levels of TNF-α in their blood.
View Article and Find Full Text PDFBiomaterial-based strategies for primary human corneal endothelial cells for therapeutic applications: from cell expansion to transplantable carrier.
Biomater Sci
January 2025
Department of Chemical Engineering, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.
The treatment of corneal blindness due to corneal diseases and injuries often requires the transplantation of healthy cadaveric corneal endothelial graft tissue to restore corneal clarity and visual function. However, the limited availability of donor corneas poses a significant challenge in meeting the demand for corneal transplantation. As a result, there is a growing interest in developing strategies alleviate this unmet need, and one of the postulated approaches is to isolate and expand primary human corneal endothelial cells (HCECs) for use in cell therapy.
View Article and Find Full Text PDFDetermination of reference intervals of venous blood gas and acid-base parameters in clinically healthy awake cats.
J Vet Emerg Crit Care (San Antonio)
January 2025
Department of Veterinary Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Background: Venous blood gas and acid-base analysis is often performed in cats and requires appropriate reference intervals (RIs) for interpretation. The currently available RIs were created from small numbers of cats, while current guidelines suggest that a minimum number of 40 samples is required for the creation of an accurate/appropriate RI.
Key Findings: In 41 healthy awake cats, pH, PCO, PO, sodium, potassium, ionized calcium, chloride, glucose, and plasma lactate concentrations were measured, while bicarbonate, standardized base excess, and anion gap were calculated.
Geometric Study and Clinical Case Series for Mandible Reconstruction With a Single-Piece Scapular Free Flap.
Head Neck
January 2025
Division of Otolaryngology, Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Background: Virtual surgical planning (VSP) with simple cutting templates could help surgeons preoperatively plan scapula reconstructions in the vertical and horizontal orientations.
Methods: Virtually, eight defects were created in ten healthy mandibles and reconstructed with the subject-specific scapula vertically and horizontally. In the clinical series, 15 single-piece scapula mandible reconstructions planned with in-house VSP and guided with simple templates were compared with 15 freehand reconstructions.
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