Objective: To investigate the effect of flapless osteoperforation on the tissue response of the atrophic alveolar ridge affected by orthodontic tooth movement (OTM).
Materials And Methods: An atrophic alveolar ridge model was established in the mandibular quadrants of eight beagle dogs. As a split-mouth design, the quadrants were randomly divided into group C (OTM only) and group OP (OTM with flapless osteoperforation). The rate of OTM for 10 weeks was compared between groups, and micro-CT-based histomorphometric analysis and RNA-sequencing-based gene-enrichment analysis were performed targeting the atrophic ridge.
Results: Group OP displayed more rapid tooth movement with lower bone mineral density and higher trabecular fraction in the atrophic ridge than did group C, showing no intergroup difference of total ridge volume. As contributing biological functional pathways in group OP, the genes related to osteoclast differentiation and TNF signaling pathway were up-regulated and those associated with Wnt signaling pathway and AMPK signaling pathway were down-regulated.
Conclusions: Flapless osteoperforation facilitated the rate of OTM toward the atrophic ridge, maintaining low bone density, whereas it did not increase the volume of the atrophic ridge.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315703 | PMC |
| http://dx.doi.org/10.2319/061217-388.1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparison of efficacy between micro-osteoperforations and alveolar corticotomies on the rate of orthodontic tooth movement: A systematic review and meta-analysis.
J Craniomaxillofac Surg
January 2025
Universidad Europea de Valencia, Faculty of Health Sciences, Department of Dentistry, Valencia, Spain; Universidad de Valencia, Faculty of Medicine and Dentistry, Department of Orthodontics, Valencia, Spain. Electronic address:
Micro-osteoperforations and corticotomies are two surgical techniques commonly used to increase the rate of tooth movement. The aim of this systematic review was to respond to the question: Which method used for accelerating orthodontic tooth movement, micro-osteoperforations or alveolar corticotomy, produces a higher rate of tooth movement and present less adverse effects? Searches were performed in the electronic databases of PubMed, Scopus, Cochrane CENTRAL, Web of Science, Lilacs and Science Direct, as well as grey literature (Opengrey), up to March 2024. All the included studies were controlled, randomized clinical trials, cohort, case-control, cross-sectional, and multicentre studies of patients treated with orthodontics and corticotomies or micro-osteoperforations.
View Article and Find Full Text PDFLingual Arch-supported Open Coil Space Regainer.
Int J Clin Pediatr Dent
December 2024
Department of Orthodontics and Dentofacial Orthopedics, JMF's ACPM Dental College, Dhule, Maharashtra, India.
Aim And Background: The lingual arch has been widely used as a space maintainer in the lower arch during the mixed dentition phase, and the open-coil space regainer (OCSR) has been used for localized space regaining. However, an appliance consisting of both has not been previously documented. This case report highlights the advantages of using a lingual-arch-supported OCSR for regaining lost space.
View Article and Find Full Text PDFDentoalveolar and Skeletal Effects of an Anterior Open Bite Treatment Protocol Using Zygomatic Anchorage.
Orthod Craniofac Res
January 2025
Department of Orthodontics, Dental School, Okan University, Istanbul, Turkey.
Objective: Primary aim was to analyse dentoalveolar and skeletal effects induced by an anterior open bite (AOB) treatment protocol for intrusion of maxillary buccal segment. Secondary aim was to investigate whether a subsequent change occurred in hyoid position.
Materials And Methods: Study group included 28 non-growing subjects treated in academic setting for correction of AOB.
[Clinical efficacy of clear aligner treatment for pathologically migrated teeth in the anterior region of patients with severe periodontitis].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2025
Department of Orthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.
Objective: To evaluate the clinical efficacy of clear aligner therapy in patients with severe periodontitis accompanied by pathological tooth displacement in the anterior region.
Methods: This retrospective study analyzed patients diagnosed with severe periodontitis and pathological displacement in the anterior region, who visited both the Periodontics and Orthodontics Departments at Peking University School and Hospital of Stomatology between 2019 and 2022. A total of 26 eligible cases were included in this study.
Biomechanical and Biological Multidisciplinary Strategies in the Orthodontic Treatment of Patients with Periodontal Diseases: A Review of the Literature.
Bioengineering (Basel)
January 2025
Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, 95124 Catania, Italy.
Orthodontic treatment aims to correct malocclusions and ensure the overall health and stability of the periodontium. The relationship between orthodontic therapy and periodontal health is intricate and multifaceted, and a comprehensive approach is often required to achieve optimal outcomes. Firstly, this article delves into the impact of orthodontic mechanics on periodontal tissues, emphasizing the importance of minimizing iatrogenic effects such as root resorption and gingival recession.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!