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Bone Tissue Engineering With Chitosan, Carbon Nanotubes, and Hydroxyapatite Biomaterials Enriched With Mesenchymal Stem Cells: A Radiographic and Histological Evaluation in a Sheep Model Undergoing Ostectomy (Bone Tissue Engineering in a Sheep Model).
J Biomed Mater Res B Appl Biomater
January 2025
Department of Surgery, School of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP), São Paulo, SP, Brazil.
Comminuted fractures associated with tissue loss can adversely affect bone regeneration. Biomaterials enriched with mesenchymal stem cells (MSCs) employed for supporting osteosynthesis and potentiating osteoconduction are necessary to fill these bone defects. Natural compound biomaterials, similar to bone tissue, have been extensively tested in animal models for clinical use.
View Article and Find Full Text PDFOrthoplastic Reconstruction of Distal Tibia High-Energy Fractures Using a Circular External Fixator-A Systematic Review.
J Clin Med
September 2024
Faculty of Medicine, "Transilvania" University, 500036 Brasov, Romania.
Article Synopsis
- Compound fractures of the distal tibia present significant challenges for orthopedic and plastic surgeons due to limited soft tissue options and complex fracture patterns.
- A study conducted following PRISMA guidelines reviewed 3355 articles, ultimately selecting 14 with 283 participants; it highlighted variability in bone loss (0.7 to 18.2 cm) and soft tissue defects (3/3 cm to 16/21 cm), but showed successful treatment methods.
- The findings emphasize the importance of an orthoplastic team, recommending the use of Ilizarov external fixators combined with flap reconstruction for effective treatment and reduced complications in high-energy tibia trauma cases.
Nutrient Composition and Flavor Profile of Crucian Carp Soup Utilizing Fish Residues through Comminution and Pressure-Conduction Treatment.
Foods
March 2024
SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Collaborative Innovation Center of Seafood Deep Processing, Liaoning Province Collaborative Innovation Center for Marine Food Deep Processing, Dalian Technology Innovation Center for Chinese Prepared Food, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
In conventional fish soup processing, valuable aquatic resources like fish skins, bones, and scales are often squandered. This study was aimed at investigating if comminution combined with pressure-conduction treatment has the potential to enhance the reutilization of cooking residues. The different blending ratios of original soup (OS), made from the initial cooking of fish, and residue soup (RS), produced from processed leftover fish parts, were alternatively investigated to satisfy the new product development.
View Article and Find Full Text PDFPhysicochemical Properties of Dried and Powdered Pear Pomace.
Molecules
February 2024
Department of Molecular Biology and Genetics, Faculty of Science and Art, Bingöl University, 12000 Bingöl, Türkiye.
Pear pomace, a byproduct of juice production, represents a valuable reservoir of bioactive compounds with potential health benefits for humans. This study aimed to evaluate the influence of drying method and temperature on pear pomace, specifically focusing on the drying kinetics, grinding characteristics, color, phenolic profile (LC-MS/MS), and antioxidant activities of the powder. Drying using the contact method at 40 °C with microwave assistance demonstrated the shortest duration, whereas freeze-drying was briefer compared to contact-drying without microwave assistance.
View Article and Find Full Text PDFBiomechanical evaluation of novel intra- and extramedullary assembly fixation for proximal humerus fractures in the elderly.
Front Bioeng Biotechnol
October 2023
The Department of Orthopaedic Trauma, Chinese PLA General Hospital (301 Hospital), Beijing, China.
A novel intra- and extramedullary assembly fixation method was introduced, which achieved good clinical results in complex proximal humeral fractures; however, evidence of its comparability with traditional fixation is lacking. This biomechanical study aimed to compare it with traditional fixation devices in osteoporotic proximal humeral fractures. Three-part proximal humeral fractures with osteopenia were created on 12 pairs of fresh frozen humerus specimens and allocated to three groups: 1) lateral locking plate, 2) intramedullary nail, and 3) intra- and extramedullary assembly fixation.
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