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Association of Waist Circumference Gain and Incident Prediabetes Defined by Fasting Glucose: A Seven-Year Longitudinal Study in Beijing, China. | LitMetric

AI Article Synopsis

  • This study explored the link between waist circumference (WC) gain and the risk of prediabetes in Chinese adults, using data from over 7,900 health check-up participants from 2009 to 2016.
  • The results showed that those with a WC gain of more than 5% had a significantly higher risk of developing prediabetes compared to those who lost waist size or maintained it.
  • The findings highlight the importance of lifestyle changes to prevent abdominal obesity, which could help reduce the rising rates of prediabetes and related health issues in China.

Article Abstract

The risk of incident prediabetes with gain in waist circumference (WC) has not been addressed among Chinese adults. A total of 7951 participants who underwent health check-ups at the Beijing Physical Examination Center and Beijing Xiaotangshan hospital were recruited in 2009 and followed up in 2016. Participants were classified into four groups according to categories of percent WC gain: ≤-2.5%, -2.5-2.5%, 2.5-5%, and >5%. The effect of WC gain on prediabetes was evaluated using modified Poisson regression models. Over seven years of follow-up, we identified 1034 prediabetes cases (413 women). Compared with a WC gain of ≤-2.5%, participants with a WC gain of >5% have a higher risk of prediabetes, be they male (non-abdominal obesity at baseline group: RR = 1.57, 95% CI: 1.10-2.24, abdominal obesity at baseline group: RR = 1.66, 95% CI: 1.20-2.30) or female (non-abdominal obesity at baseline group: RR = 1.74, 95% CI: 1.14-2.64, abdominal obesity at baseline group: RR = 2.47, 95% CI: 1.43-4.28). In conclusion, the risk of prediabetes increased significantly with increasing WC for both genders in the Chinese population. Lifestyle interventions aiming at preventing abdominal obesity are urgently needed to reduce the increasing burden of prediabetes, diabetes, and its complications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664709PMC
http://dx.doi.org/10.3390/ijerph14101208DOI Listing

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