Central line associated bloodstream infection (CLABSI) reduction programmes in hospitalised children have been focused in the intensive care setting and little data is available on the efficacy and cost effectiveness of such programmes in other clinical areas. Prospective monitoring of hospital acquired CLABSI rates in all clinical areas was performed at Alder Hey Children's Hospital for a period of three years following the implementation of a central venous line (CVL) care bundle. We observed a decrease in CLABSI rates from 220 in the first year following intervention to 108 per 100,000 patient days (=0.002) in the third year of the study, demonstrating a decrease of over 50% in CLABSI rates. Blood culture contamination rates were also significantly reduced. The introduction of a CVL care bundle produced a significant, sustainable reduction in hospital acquired CLABSI rates in a children's hospital setting.
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http://dx.doi.org/10.1177/1757177413520186 | DOI Listing |
Interdiscip Cardiovasc Thorac Surg
January 2025
Division of Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Overusing blood cultures (BCxs) can lead to false positives, unnecessary antibiotics, and increased healthcare costs. Despite studies on inpatient BCx algorithms, none have focused on cardiothoracic surgery (CTS) patients, with complex postoperative care and invasive devices. This study aimed to evaluate the impact of a BCx algorithm on BCx event (BCE) rates in CTS step-down units.
View Article and Find Full Text PDFInfect Dis Clin Microbiol
December 2024
Department of Pediatric Intensive Care Unit, Dr. Behçet Uz Children's Diseases and Surgery Training and Research Hospital, İzmir, Türkiye.
Objective: We aimed to discuss our experience of a higher incidence of catheter-associated bloodstream infections (CLABSIs) during the needle-free connector (NFC) and single-use prefilled flushing syringe (PFS) shortage.
Materials And Methods: Retrospective analyses were carried out to investigate the CLABSI rates at a tertiary training hospital from January 1, 2023, to December 31, 2023, and the study period included a three-month shortage of NFCs and PFSs in April and June 2023.
Results: The CLABSI rate for the three months was 5.
J Pediatr
December 2024
Department of Pediatrics, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Department of Cardiology, Boston Children's Hospital, Boston, MA, USA; Children's Hospital at Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia; Sandra L. Fenwick Institute for Pediatric Health Equity and Inclusion, Boston Children's Hospital, Boston, MA, USA. Electronic address:
Objective: To study pediatric inpatient hospital capacity and resources, characterizing differences according to social determinants of health (SDoH) using market share techniques.
Study Design: This cross-sectional study uses non-elective inpatient discharges (≥1 month to ≤19 years) from Healthcare Cost and Utilization Project and American Hospital Association surveys to derive hospital capacity and resources/capability. We include US hospitals with ≥1 pediatric bed and ≥1 pediatric discharge and calculate per bed capital, expenditure, and staffing, transfer rates, payer-mix, and adjusted central line-associated blood stream infection (CLABSI) rate.
Qual Manag Health Care
December 2024
Author Affiliation: Quality Improvement, M Health Fairview University of Minnesota Medical Center, Minneapolis, Minnesota.
Background: Bundled interventions and auditing have been recommended to reduce central line-associated bloodstream infection (CLABSI) events at acute care hospitals. We review the outcomes of a bundle audit program at an adult and pediatric academic medical center from April 1, 2021, to May 31, 2022.
Objectives: To analyze the impact on CLABSI rates following the introduction of a central line maintenance bundle audit process.
Infect Control Hosp Epidemiol
December 2024
BC Children's & BC Women's Hospitals, Vancouver, BC, Canada.
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