This study was conducted to develop and test a prediction model that explains health-related quality of life (HRQoL) of patients with Parkinson's disease (PD). Participants were 248 patients with PD enrolled in the neurology clinic of a university hospital in Seoul, Korea. The data were collected through structured questionnaires from March 1 to July 5, 2013. Motor fluctuations, depression, sleep disturbances, fatigue, and activities of daily living had significant direct effects on the quality of life of PD patients. Disease severity, social support, pain, sleep disturbances, fatigue, and activities of daily living had significant indirect effects on patients' quality of life. These predictive variables explained 77.4% of the total variance. The assessment of HRQoL in PD should be considered along with the variables affecting it, including social support. In addition, strategies to enhance social support may be useful for improving the quality of life for patients with PD.
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http://dx.doi.org/10.1016/j.gerinurse.2017.09.001 | DOI Listing |
JMIR Res Protoc
March 2025
Paseo de los Encomendadores, Faculty of Health Sciences, University of Burgos, Burgos, Spain.
Background: Breast cancer is the second most common cancer in women worldwide. Treatments for this disease often result in side effects such as pain, fatigue, loss of muscle mass, and reduced quality of life. Physical exercise has been shown to effectively mitigate these side effects and improve the quality of life in patients with breast cancer.
View Article and Find Full Text PDFRes Aging
March 2025
Labour Institute for Economic Research LABORE, IZA Institute of Labor Economics, University of Jyväskylä, Helsinki, Finland.
Ageing populations foreground understanding how retirement affects quality of life. The inconclusive findings on retirement's quality of life impacts encourage further analyses of this association's complexity. Using waves 4 (2011) and 6 (2015) of the Survey of Health, Ageing and Retirement in Europe ( = 9249) and conditional change multilevel mixed-effects linear regressions, this study investigates how changes in three measures of social network involvement (size of close social network, frequency of contact with one's close social network, and emotional closeness with one's close social network) moderate how retirement is associated with quality of life.
View Article and Find Full Text PDFFood Addit Contam Part A Chem Anal Control Expo Risk Assess
March 2025
Food Toxicology and Contaminants Department, National Research Centre, Giza, Egypt.
Citrus fruits, known for their vibrant flavours and health benefits, are susceptible to fungal attacks, particularly from toxigenic fungi, which pose a significant pre- and post-harvest hazard. However, aromatic oils and their nanoparticles may effectively address this issue. Marjoram and fennel oils, alongside their nanoparticles, were extracted, and their aromatic constituents and antimicrobial activities were evaluated.
View Article and Find Full Text PDFEuropace
March 2025
Clinical Cardiac Academic Group, Genetic and Cardiovascular Sciences Institute, City-St George's University of London, London, UK.
Atrial fibrillation (AF) is one of the most common cardiac diseases and a complicating comorbidity for multiple associated diseases. Many clinical decisions regarding AF are currently based on the binary recognition of AF being present or absent with the categorical appraisal of AF as continued or intermittent. Assessment of AF in clinical trials is largely limited to the time to (first) detection of an AF episode.
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