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Objective: Aim: To give epidemiological and clinical characteristics of the morbidity of Lyme borreliosis in Ivano-Frankivsk region for the period of 2000-2022 years.
Patients And Methods: Materials and Methods: There were used annual reports (form №1) from the State Institution "Ivano-Frankivsk Regional Center for Disease Control and Prevention of the Ministry of Health of Ukraine" and 200 of "Medical records of inpatients" (form 003/о) of the Ivano-Frankivsk Regional Clinical Infectious Diseases Hospital for 2000-2022 years.
Results: Results: The morbidity of Lyme borreliosis in the Ivano-Frankivsk region has been permanently increasing since 2000.
Adverse event profile of albumin-bound paclitaxel: a real-world pharmacovigilance analysis.
Front Pharmacol
October 2024
Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, Sichuan, China.
Background: Abraxane plays a crucial role in the treatment of various types of cancer, despite the considerable attention it has garnered for its adverse drug events (ADEs). Nevertheless, there is currently a significant lack of comprehensive real-world pharmacovigilance studies on the ADEs associated with Abraxane.
Methods: We conducted a retrospective analysis of ADEs associated with Abraxane using data mining from the FAERS database, analyzing data from 2005 to 2023.
Erythroderma in the elderly.
J Dermatol
November 2024
Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
Erythroderma is the end-stage condition caused by various inflammatory diseases, presenting with widespread generalized coalesced erythema on the trunk and extremities. Erythroderma is not a disease itself, but rather is a symptom expressing erythrodermic condition, which is frequently associated with inguinal lymphadenopathy, chills, and mild fever. The clinical characteristics include sparing the folds of the trunk and extremities (deck-chair sign), and cobblestone-like disseminated grouping prurigo; however, the deck-chair sign is not specific to papulo-erythroderma (Ofuji disease).
View Article and Find Full Text PDFFatal borealpox in an immunosuppressed patient treated with antivirals and vaccinia immunoglobulin - Alaska, 2023.
Clin Infect Dis
November 2024
Section of Epidemiology, Alaska Division of Public Health, Anchorage, Alaska, USA.
Background: Borealpox virus (BRPV, formerly known as Alaskapox virus) is a zoonotic member of the Orthopoxvirus genus first identified in a person in 2015. In the six patients with infection previously observed BRPV involved mild, self-limiting illness. We report the first fatal BRPV infection in an immunosuppressed patient.
View Article and Find Full Text PDFDetection of Borrelia burgdorferi sensu lato by proteomics: a complementary diagnosis tool on erythema migrans biopsies.
Clin Microbiol Infect
January 2025
UR3073-Pathogen-Host- Arthropod Vectors Interactions-Group Borrelia, Fédération de Médecine Translationnelle, Université de Strasbourg, Strasbourg, France; French National Reference Center for Borrelia, Hôpitaux Universitaires de Strasbourg, Strasbourg, France. Electronic address:
Objectives: We have developed targeted proteomics in the context of Lyme borreliosis (LM) as a new direct diagnostic tool for detecting Borrelia proteins in the skin of patients with erythema migrans. If satisfactory, this proteomic technique could be used in addition to culture and/or PCR for disseminated infections where Borrelia detection is essential to demonstrate active infection. In these infections, the diagnosis is indirect and relies mainly on serology.
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