AI Article Synopsis
- Sedatives and analgesics are commonly used during colonoscopies, but there is a risk of complications affecting vital signs, which this study aimed to further understand.
- The research analyzed data from 755 patients and found that 17% experienced fluctuations in vital signs, with hypotension in 13% and oxygen desaturation in 5%, yet no patients required hospitalization.
- Important risk factors identified for vital sign fluctuations included older age, being female, and the use of midazolam as a sedative.
Article Abstract
Background: Sedatives or analgesics are widely used to relieve a patient's discomfort during colonoscopy (CS). Although cardiopulmonary adverse events are sometimes experienced during the examination, the risk factors for vital signs fluctuation (VSF) have not been fully elucidated. This study thus aimed to identify the risk factors for VSF during the examination, as well as to evaluate the frequency and the degree of VSF.
Summary: A total of 755 consecutive subjects who received CS under endoscopist-administrated sedation using midazolam, meperidine, or combination of both were retrospectively analyzed. We assessed the distribution of vital signs during the procedure and frequency of VSF. To identify independent risk factors, we analyzed the association between VSF and subjects' characteristics and procedure information using the multivariate logistic regression model. Consequently, VSF was observed in 17% of all; hypotension and oxygen desaturation was observed in 13 and 5%, respectively. However, we could achieve the purpose of all procedure and, no one required hospitalization or extension of hospital stay. Multivariate analysis revealed that age (OR 1.05 [95% CI 1.04-1.07]), being female (OR 1.78 [95% CI 1.19-2.70]), and use of midazolam (OR 5.06 [95% CI 3.18-8.08]) were independent risk factors for VSF.
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| http://dx.doi.org/10.1159/000481343 | DOI Listing |
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