The authors present the results of domestic clinical trials on the efficacy and safety of mexidol in patients with cerebrovascular disorders including ischemic stroke (IS). The use of mexidol is associated with complete and rapid regression of the focal neurological deficit. Mexidol is well tolerated with no significant side-effects. The drug is recommended for enteral and parenteral administration in patients with IS.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.17116/jnevro20171178275-80 | DOI Listing |
Surg Today
January 2025
Department of Basic Medical Science, College of Medicine, Taibah University, Madinah, Saudi Arabia.
Anorectal fistulas remain one of the most challenging conditions in colorectal surgery and require precise anatomical knowledge for successful management. This comprehensive review synthesizes the current evidence on the anatomical foundations of fistula development and treatment, particularly focusing on the cryptoglandular hypothesis and its clinical implications. A systematic analysis of the recent literature has examined the relationship between anatomical structures and fistula formation, classification systems, diagnostic modalities, and therapeutic approaches.
View Article and Find Full Text PDFBr J Math Stat Psychol
January 2025
Departments of Psychology and Statistics, University of Illinois Urbana-Champaign, Champaign, Illinois, USA.
Item response theory models are commonly adopted in educational assessment and psychological measurement. Such models need to be modified to accommodate practical situations when statistical sampling assumptions are violated. Omission is a common phenomenon in educational testing.
View Article and Find Full Text PDFBiotechnol Bioeng
January 2025
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, PR China.
Based on the innate sensitivity of cell to substrate topographical cues, modulating cell-directed growth behavior is crucial for promoting tissue repair and reconstruction. Although photolithography technology has been extensively employed to fabricate a variety of anisotropic patterned structures to guide cell growth, it remains a great challenge to design high-resolution micro/nano hierarchical structures directly onto medical titanium (Ti)-based implants. Herein, we present a rapid, reliable and reproducible approach combining photolithography and hydrothermal technology to construct a micro/nano hierarchical structure including anisotropic micro-strips and a porous structure composed of TiO nanotubes features.
View Article and Find Full Text PDFJ Sci Food Agric
January 2025
Department of Food Science and Nutrition, School of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.
Background: The loss of flavor in modern tomato cultivars represents a great challenge for the food industry. This study investigated the potential of power ultrasound as an innovative approach to improve tomato juice flavor by releasing bound volatiles.
Results: It was found that power ultrasound offered a more viable, environmentally friendly technique for enhancing the aroma of tomato juice compared with enzymatic or acid hydrolysis methods.
Org Biomol Chem
January 2025
Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China.
Multi-component reactions (MCRs) are processes in which three or more reactants are introduced into one pot to obtain the final product with high atom efficiency, and in recent years, these have become a key strategy for advancing more sustainable processes in modern synthetic communities and the pharmaceutical industry. Meanwhile, minimizing the use of solvents, catalysts, time, reagents, and waste is essential during green chemical synthesis to reduce cost and environmental impact. Heterocycles are ubiquitous and have thus prompted the development of numerous methods for their synthesis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!