AI Article Synopsis
- Nicolau syndrome is a rare complication that can occur after receiving certain drug injections, traditionally reported with various types of injections but not previously associated with intramatricial injections.
- An 18-year-old male experienced Nicolau syndrome after seven intramatricial injections, leading to symptoms that required treatment with antibiotics, vasodilators, analgesics, and daily dressings.
- The patient's condition improved significantly, with complete resolution of symptoms and color return to the affected digit by day 21, highlighting the need for awareness among dermatologists regarding this syndrome.
Article Abstract
Nicolau syndrome (Embolia cutis medicamentosa) is a rare complication following parenteral administration of a drug. It has been reported in association with intramuscular, subcutaneous, intravenous and intra-articular injections. However, Nicolau syndrome following intramatricial injection has not been described to the best of our knowledge. We report the case of an 18-year-old male who developed this complication following 7 session of intramatricial injection. The patient was started on broad spectrum antibiotic coverage, vasodilator therapy, analgesics, and daily dressing. On day 21, the symptoms completely resolved with return of normal color of the digit. The case is being reported to make dermatologists aware of the possibility of Nicolau syndrome following intramatricial injection of triamcinolone acetonide.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621196 | PMC |
| http://dx.doi.org/10.4103/idoj.IDOJ_333_16 | DOI Listing |
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