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http://dx.doi.org/10.1111/den.12971 | DOI Listing |
Med Phys
January 2025
Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Background: Diffusing alpha-emitters Radiation Therapy ("Alpha DaRT") is a promising new radiation therapy modality for treating bulky tumors. Ra-carrying sources are inserted intratumorally, producing a therapeutic alpha-dose region with a total size of a few millimeter via the diffusive motion of Ra's alpha-emitting daughters. Clinical studies of Alpha DaRT have reported 100% positive response (30%-100% shrinkage within several weeks), with post-insertion swelling in close to half of the cases.
View Article and Find Full Text PDFSci Total Environ
January 2025
Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, Guangdong, China; Guangdong Medical University, Dongguan, Guangdong, China; Guangdong Pharmaceutical University, Guangzhou, Guangdong, China; Southern Medical University, Guangzhou, Guangdong, China; JI NAN University, Guangdong, China. Electronic address:
Background: Noise is a threat to human auditory system, hearing protection devices (HPDs) are widely used to prevent noise-induced hearing loss (NIHL). However, the role of wearing HPDs on NIHL and the complex relationship between them are still unclear. This study aims to explore such relationship and identify the associated influencing pathways.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
January 2025
Department of Neurosurgery, Faculty of Medicine, Azad Tehran University of Medical Sciences, Tehran, Iran.
Background: Pedicle screw insertion in posterior spinal surgery can cause vascular injuries, including rare intercostal artery pseudoaneurysms, which are typically discovered incidentally during reimaging. Onyx embolization is an effective treatment for small artery pseudoaneurysms.
Observations: A 36-year-old man who had initially presented with back pain that remained unresponsive to nonsteroidal anti-inflammatory drugs was diagnosed with a T7-8 sarcomatous lesion confirmed by magnetic resonance imaging and biopsy.
Biochemistry
January 2025
Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Sector 81, SAS Nagar, Manauli, Mohali, Punjab 140306, India.
Listeriolysin O (LLO) is a potent membrane-damaging pore-forming toxin (PFT) secreted by the bacterial pathogen . LLO belongs to the family of cholesterol-dependent cytolysins (CDCs), which specifically target cholesterol-containing cell membranes to form oligomeric pores and induce membrane damage. CDCs, including LLO, harbor designated pore-forming motifs.
View Article and Find Full Text PDFActa Bioeng Biomech
September 2024
Department of Mechanics, Materials and Biomedical Engineering, Faculty of Mechanical Engineering, Wrocław University of Science and Technology, Wrocław, Poland.
: The aim of this study was to evaluate the abrasive wear of the sliding screw-rod joint used in growth guidance system (GGS) stabilizers, allowing for the translation of the screw along the rod during the spinal growth process in a standard and modified system. : The study used single kinematic screw-rod pairs made of titanium alloy Ti6Al4V. Mechanical tests (cyclic loads) simulated the stabilizer's operation under conditions similar to actual use.
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