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Endocr Connect
January 2025
A Buha Djordjevic, Department of Toxicology, University of Belgrade Faculty of Pharmacy, Belgrade, Serbia.
Endocrine-disrupting chemicals (EDCs) are significant contributors to various detrimental conditions, mechanistically disrupting the endocrine system and causing adverse health effects. Mounting evidence suggests they can induce multigenerational and transgenerational effects, yet awareness among individuals remains insufficient. This study aimed to assess the knowledge, attitudes, and ways of informing moms in Serbia about endocrine disruptors based on information from 190 women in Serbia.
View Article and Find Full Text PDFFront Chem
January 2025
Institute of Materials Research, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, Guangdong, China.
Bisphenol A (BPA) poses a significant environmental threat due to its widespread use as an industrial chemical and its classification as an environmental endocrine disruptor. The urgent need for effective BPA removal has driven research toward innovative solutions. In this study, we present the synthesis and application of a novel 2D-3D spherically hierarchical ZnInS (ZIS) photocatalyst for the photocatalytic degradation of BPA under visible light for the first time.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Department of Endocrinology and Metabolism, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Objective: This study aims to investigate the associations between rs724030 A>G variant and prediabetes risk, along with their correlations with clinical features, including plasma glucose and serum insulin levels during oral glucose tolerance test (OGTT), islet function, insulin resistance, and plasma lipid levels. In particular, we investigated whether there are sex dimorphisms in the impact of this variant on islet function/insulin resistance.
Methods: We included 3415 glucose-tolerant healthy and 1744 prediabetes individuals based on OGTT.
Int J Biol Macromol
January 2025
Precision Medicine Center, Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China. Electronic address:
The use of natural products for cancer treatment has a lengthy history. The safety and multifunctionality of naturally occurring substances have rendered them appropriate for cancer treatment. Curcumin influences multiple molecular pathways and is advantageous for treating both hematological and solid tumors.
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January 2025
Safety Assessment, Syngene International Limited, Biocon Park, Bommasandra IV Phase, Jigani Link Road, Bangalore, 560099, Karnataka, India.
Acovenoside A, a cardenolide glycoside from Acokanthera oppositifolia, demonstrates significant therapeutic potential in cardioprotection and oncology, particularly against non-small cell lung cancer (NSCLC). However, its toxicological profile requires thorough evaluation for safe pharmaceutical application. For this purpose a comprehensive in silico methods were applied, including ACD/Labs Percepta, STopTox, admetSAR 3.
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