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Cardiopulmonary arrest in liver transplantation surgery: Perioperative beta-blockade implication in the cirrhotic patient.
Rev Esp Anestesiol Reanim (Engl Ed)
January 2025
Hospital Universitario Gregorio Marañón, Madrid, Spain.
Liver transplantation (LT) has an incidence of intraoperative cardiopulmonary arrest (CPA) of around 5%. Patients who experience CPA during this procedure have a reduced survival rate of approximately 50%. Most CPAs occur during the neohepatic phase due to reperfusion syndrome, but this is not always the underlying cause, and a broad differential diagnosis must be performed.
View Article and Find Full Text PDFHow To Improve Patient Selection in Individuals With Lower Extremity Amputation Using a Bone-anchored Prosthesis.
Clin Orthop Relat Res
January 2025
Department of Rehabilitation, Radboud University Medical Center, Nijmegen, the Netherlands.
Background: Many patients with a lower limb socket-suspended prothesis experience socket-related problems, such as pain, chronic skin conditions, and mechanical problems, and as a result, health-related quality of life (HRQoL) is often negatively affected. A bone-anchored prosthesis can overcome these problems and improve HRQoL, but these prostheses have potential downsides as well. A valid and reliable tool to assess potential candidates for surgery concerning a favorable risk-benefit ratio between potential complications related to bone-anchored prostheses and improvements in HRQoL is not available yet.
View Article and Find Full Text PDFObjective: Cervical degeneration involves many pathophysiological changes. Vertebral bone loss, sclerotic hyperplasia of the vertebral body and intervertebral disc degeneration (IDD) are most common degenerative factors. However, whether there is a correlation between changes in vertebral bone mass and IDD remains unclear.
View Article and Find Full Text PDFBackground And Aims: Pectus carinatum (PC) is the second most common deformity of the anterior chest wall, resulting in detrimental effects on body image and quality of life. This study evaluated the safety, effectiveness, and factors associated with the treatment of PC using a sandwiched bar and screw fixation system, first performed in Vietnam at the University Medical Center Ho Chi Minh City in 2016.
Methods: This retrospective cohort study was conducted from March 2016 to February 2023 in patients with PC and PC-mixed pectus excavatum (PE) deformities.
Irreversible Electroporation and β-Glucan Induced Trained Innate Immunity for the Treatment of Pancreatic Ductal Adenocarcinoma: A Phase II Study.
J Am Coll Surg
January 2025
Division of Immunotherapy, The Hiram C. Polk Jr., MD Department of Surgery, Immuno-Oncology Program, Brown Cancer Center, University of Louisville School of Medicine, Louisville, KY, USA.
Introduction: Irreversible electroporation(IRE) has augmented the effects of certain immunotherapies in pancreatic cancer(PDA). Yeast-derived particulate beta-glucan induces trained innate immunity and has successfully reduces murine PC tumor burden. This is a Phase II study to test the hypothesis that IRE may augment beta-glucan induced trained immunity in patients with PDA.
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