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Parathyroid Carcinoma Complicated by Parathyromatosis and Refractory Hypercalcemia.
Cureus
October 2024
Department of Endocrinology Diabetes Medicine, Samatvam Diabetes Endocrinology and Medical Center Samatvam: Science and Research for Human Welfare Trust, Bangalore, IND.
Parathyroid carcinoma (PC) is a rare malignancy. In January 2022, a 41-year-old woman presented with weight loss, proximal muscle weakness, and bone pain. She was diagnosed with severe hypercalcemia with serum calcium of 15.
View Article and Find Full Text PDFParathyroid fine needle aspiration with PTH washout: Can it lead to parathyroid cell seeding in primary hyperparathyroidism?
Medicine (Baltimore)
April 2024
Bulent Ecevit University School of Medicine, Department of General Surgery, Zonguldak, Turkey.
Although parathyroid fine-needle aspiration (P-FNA) with parathyroid hormone (PTH) washout is effective in detecting preoperative parathyroid lesions, it also presents risks such as fibrosis, hematoma, and, in rare cases, tumor seeding. This study aimed to investigate whether P-FNA with PTH washout leads to the seeding of parathyroid cells along the path of the needle. A retrospective analysis was conducted on patients undergoing minimally invasive parathyroidectomy guided by preoperative PTH washout.
View Article and Find Full Text PDFA case of mediastinal hyperparathyromatosis.
J Surg Case Rep
January 2024
Department of Pathology, Beaumont Hospital, Beaumont Road, Beaumont, Dublin 9, D09V2N0, Ireland.
Recurrent hyperparathyroidism (HPT) after initial parathyroid surgery occurs rarely in an ectopic location. The rare phenomenon of parathyromatosis may be the cause of this. We present the case of a 59-year-old woman with recurrent HPT, which presented as a new ectopic mediastinal parathyroid gland 13 years after initial 3.
View Article and Find Full Text PDFLate recurrence of a single gland primary hyperparathyroidism-Atypical parathyroid adenoma or misdiagnosed parathyroid carcinoma.
Clin Case Rep
January 2024
Department of Gastroenterology, Endocrinology, Diabetology and General Medicine, Klinikum Kassel Kassel Germany.
Key Clinical Message: This case report aims to raise awareness of differential diagnoses of hypercalcemia and primary hyperparathyroidism, including parathyroid carcinoma and atypical adenoma, and to highlight the diagnostic challenges.
Abstract: Parathyroid carcinoma is a rare and often fatal cause of primary hyperparathyroidism and hypercalcemia. To date, there is still no clear-cut diagnostic pathway for parathyroid carcinoma established, which results in major diagnostic ambiguity and complexity.
Intractable Parathyromatosis despite extensive surgical interventions: A case report with literature review.
Int J Surg Case Rep
January 2024
King Saud Medical City, Riyadh 12745, Saudi Arabia.
Introduction And Importance: Parathyromatosis is a very rare condition where persistent hyperparathyroidism occurs after surgical excision of the parathyroid gland. That is explained by many theories mainly a seeding of parathyroid gland tissue post parathyroidectomy. We report a rare case presentation of Parathyromatosis and the clinical course with the consequences of her condition.
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