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Editorial: Emerging technologies for viability enumeration of live microorganisms.
Front Microbiol
January 2025
Eurofins Microbiology, Inc., Madison, WI, United States.
Epidemiology of Methicillin-resistant Colonization in Neonates within Neonatal Intensive Care Units: A Systematic Review and Meta-analysis.
J Glob Infect Dis
December 2024
Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Introduction: Methicillin-resistant (MRSA) colonization in neonatal intensive care units (NICUs) is a significant global health concern, leading to severe infections, extended hospital stays, and substantial economic burdens on health-care systems. To develop effective infection control strategies, we need to fill existing gaps in our understanding of MRSA epidemiology in neonates. The aim of this systematic review is to provide an extensive analysis of the proportion of MRSA colonizations in NICUs.
View Article and Find Full Text PDFComparative efficacy of repurposed drugs lopinavir-ritonavir and darunavir-ritonavir in hospitalised COVID-19 patients: insights from a tertiary centre cohort.
Front Cell Infect Microbiol
January 2025
Department of Infectious Diseases, Infectious Diseases and Pulmonology Clinical Hospital, Timisoara, Romania.
Background: Drug repurposing has become a widely adopted strategy to minimise research time, costs, and associated risks. Combinations of protease inhibitors such as lopinavir and darunavir with ritonavir have been repurposed as treatments for COVID-19. Although lopinavir-ritonavir (LPV/r) and darunavir-ritonavir (DRV/r) have shown efficacy against COVID-19, the results in human studies have been inconsistent.
View Article and Find Full Text PDFClinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study.
Front Cell Infect Microbiol
January 2025
Department of Clinical Laboratory, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Background: Though droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with discrepant diagnostic performance. Additionally, there is still a lack of clinical data to reveal the association between pathogen loads detected by ddPCR and corresponding BSIs.
Methods: In this prospective study, 173 patients with suspected BSIs were enrolled.
Mpox Virus as a Global Public Health Emergency: A Scoping Review.
Can J Infect Dis Med Microbiol
January 2025
Department of Biomedical and Clinical Sciences, Division of Molecular Medicine and Virology, Linköping University, Linköping 58183, Sweden.
The monkeypox (Mpox) virus has emerged as a global public health emergency of international concern recently. The virus that was endemic in West and Central Africa has now been reported with chains of global transmission to several countries. A scoping review was carried out from the relevant literature available from PubMed, Scopus and Web of Science.
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