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Metastatic dedifferentiated liposarcoma of the mediastinum with osteosarcomatous differentiation: A case report.
Medicine (Baltimore)
December 2024
Department of Ultrasound, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Article Synopsis
- Liposarcoma is a rare malignant tumor that can occur in the mediastinum, and most existing information comes from scattered reports rather than extensive studies.
- A 51-year-old man presented with respiratory symptoms and was found to have a large mediastinal mass that was misidentified as a teratoma; after surgery, he was diagnosed with dedifferentiated liposarcoma.
- Despite surgical intervention and chemotherapy, the patient experienced rapid recurrence and ultimately died four months post-surgery, highlighting the need for correct diagnosis and treatment strategies for this aggressive condition.*
Imaging of Osteosarcoma: Presenting Findings, Metastatic Patterns, and Features Related to Prognosis.
J Clin Med
September 2024
Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Article Synopsis
- Osteosarcomas are rare bone tumors that make up less than 1% of all cancers and are most commonly found in children, second only to multiple myeloma among primary bone tumors.
- The imaging characteristics of osteosarcomas vary by histological subtype, with conventional types showing mixed radiological patterns and aggressive features, while telangiectatic forms are typically purely lytic.
- The review emphasizes the relationship between imaging features and patient outcomes, including treatment response and survival, highlighting important parameters for medical professionals involved in the management of these tumors.
Solitary Peritoneal Metastasis in Case of Osteosarcoma Detected by FDG PET/CT.
Clin Nucl Med
January 2025
Orthopaedics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- Primary osteosarcomas typically develop in the metaphyseal area of long bones, but advancements in 18F-FDG PET/CT imaging have uncovered unusual metastatic sites.
- Peritoneal deposits from osteosarcoma are rarely documented in medical literature.
- This case study discusses 18F-FDG PET/CT imaging results for a patient with osteosarcoma of the left fibula, showing isolated peritoneal metastasis without other regional or distant spread.
Role of F-FDG-PET/CT in the initial staging of very high-risk Ewing Sarcoma in a prospective multicentric Phase II Study: Is there still a place for bone marrow sampling?
Br J Cancer
November 2024
Adolescents and Young Adults Unit, Medical Oncology and SIREDO (Care, Innovation and Research for Children, Adolescents, and Young Adults with Cancer) Departments, Curie Institute, Paris, France.
Article Synopsis
- - The Ewing Sarcoma Family of Tumors (ESFT) includes rare cancers, with a significant portion showing metastatic spread, especially affecting bone and bone marrow, which worsens prognosis and necessitates stronger treatments.
- - The French phase II COMBINAIR3 study compared the effectiveness of PET/CT to traditional bone marrow aspiration and biopsy (BMAB) for staging extra-pulmonary metastatic ESFT in 42 patients.
- - Results indicated that PET/CT had high specificity (100%) and notable sensitivity (83.3%) in detecting bone marrow involvement, suggesting it can replace BMAB for initial staging, thereby enhancing treatment planning for high-risk ESFT patients.
Primary Ewing's Sarcoma of the Sternum in an Adult Male: A Rare Case Report.
J Investig Med High Impact Case Rep
October 2024
Makassed Hospital, Jerusalem, Palestine.
Article Synopsis
- * A 34-year-old man experienced chest pain misdiagnosed as muscular spasm, later discovered to have a sternal mass confirmed as Ewing's sarcoma, alongside a metastasis in his tibia.
- * The patient underwent chemotherapy followed by surgery, resulting in significant shrinkage of the tumors, and follow-up scans showed no signs of the disease, highlighting the need for prompt diagnosis and treatment of rare cancer types.
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