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Glucose Lowering through Weight management (GLoW): a randomised controlled trial of the clinical and cost effectiveness of a diabetes education and behavioural weight management programme vs a diabetes education programme in adults with a recent diagnosis of type 2 diabetes.
Diabetologia
January 2025
MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Aims/hypothesis: UK standard care for type 2 diabetes is structured diabetes education, with no effects on HbA, small, short-term effects on weight and low uptake. We evaluated whether remotely delivered tailored diabetes education combined with commercial behavioural weight management is cost-effective compared with current standard care in helping people with type 2 diabetes to lower their blood glucose, lose weight, achieve remission and improve cardiovascular risk factors.
Methods: We conducted a pragmatic, randomised, parallel two-group trial.
Regulatory Mechanisms of Signaling Pathways in Liver Cancer Treatment with Traditional Chinese Medicine.
J Ethnopharmacol
January 2025
Department of Spleen and Gastroenterology, Dongzhimen Hospital, Beijing University of Chinese Medicine,100007; Liver Diseases Academy of Traditional Chinese Medicine, Beijing University of Chinese Medicine,100029.
Ethnopharmacological Relevance: Traditional Chinese Medicine (TCM), as a longstanding therapeutic approach, offers unique advantages and potential in the treatment of liver cancer. Recent studies have highlighted its role in preventing liver cancer progression by modulating key signaling pathways. TCM's multi-component, multi-target, and multi-pathway mechanisms of action have garnered significant attention in the medical community for their ability to address complex diseases like liver cancer.
View Article and Find Full Text PDFQuality of Life and Social Health in Patients After Pancreatic Surgery.
J Gastrointest Surg
January 2025
Department of Surgery, University of Arizona, Tucson, AZ. Electronic address:
Background: Clinicians lack robust data on quality of life and social functioning after pancreatectomy limiting their ability guide patient decision-making aligned with patients' goals of care.
Methods: In this cross-sectional survey study, we administered the European Organization for Research and Treatment of Cancer Core Quality of Life questionnaire (EORTC QLQ-C30); pancreas-specific QLQ-PAN26; Patient-Reported Outcomes Measurement Information System (PROMIS™) Ability to Participate in Social Roles; and PROMIS™ Activities and social Isolation scales to all elective pancreatectomies (2021-2023). Results were compared to both normative data and between groups to determine factors predicting better QOL with a >10-12-point change considered clinically significant.
Mn-Mn Dimers Induced Multimode Emitters in Mn-Activated AZn(PO) (A = K, Rb, and Cs) with Unique [ZnPO] Chains and [ZnO] Groups.
Inorg Chem
January 2025
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China.
Mn-doped luminescent materials play a significant role in a variety of fields, including modern lighting, displays, and imaging. Mn exhibits a broad and adjustable emission, hinging on the local environment of the crystal field and the interaction of the 3d electrons. However, it is still a challenge to realize the precise control of the emission of Mn ions due to site-prior occupation in a specific lattice.
View Article and Find Full Text PDFPolymer material innovations for a green hydrogen economy.
Chem Commun (Camb)
January 2025
Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), 1 Pesek Road, Singapore 627833, Republic of Singapore.
Polymeric materials are ubiquitous in modern life. Similar to many other technological applications, polymer materials are essential in advancing the green hydrogen economy, offering solutions for hydrogen production, storage, transport, and utilization. In production, polymeric proton exchange membranes in water electrolysers enable efficient green hydrogen generation using renewable energy.
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