Heavy metals incidence in the aquatic environment and its accumulation in fish are under constant review. Gilthead seabream () specimens were exposed for two weeks to sediments highly concentrated in metals, collected at the Portman Bay (Murcia, Spain). The metals bioaccumulation was tested in liver, muscle and skin. The potential of the sediment exposure to induce variation of the stress biomarkers genes was conducted in liver and skin. Results revealed that sediments were highly contaminated with metals. However, following 2 weeks exposure to the sediments, Cd accumulates only in liver. Interestingly, the expression of the genes and were significantly down-regulated in skin. Nevertheless, gene was up-regulated only in liver. Results uphold that the stress response magnitude was organ-dependent and the skin was the most responsive tissue to metal stress conditions. These results suggest that skin should be considered as target organ for biomarkers analysis in fishes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615830 | PMC |
| http://dx.doi.org/10.1016/j.toxrep.2016.02.006 | DOI Listing |
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