To provide safe and effective products to customers in the cosmetic industry, mass spectrometry (MS) is an indispensable analytical tool. In addition to its outstanding sensitivity and specificity, the method is applicable to a wide variety of compounds, which makes it irreplaceable for the development of cosmetics, which requires the analysis of complex systems. Because most cosmetic products are applied directly to the skin and function as they are designed, monitoring the molecular compositions of endogenous or exogenous compounds in or on the skin is crucial to ensure the safety and efficacy of a cosmetic product. Recent advancements in MS and ionization techniques, such as MS imaging and ambient ionization, now provide access to richer and deeper molecular information with less time and effort. This brief review discusses advanced ionization techniques that are currently used in the field of cosmetic science using two examples, namely, the use of desorption electrospray ionization and zero-volt paperspray ionization to detect trace molecules in or on human skin.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610958 | PMC |
| http://dx.doi.org/10.5702/massspectrometry.S0071 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative evaluation of two dose-volume histogram prediction tools for treatment planning: Treatment planning quality and dose verification accuracy.
Tech Innov Patient Support Radiat Oncol
March 2025
Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Tokushima 770-8503, Japan.
Purpose: This study aims to compare treatment plans created using RapidPlan and PlanIQ for twelve patients with prostate cancer, focusing on dose uniformity, dose reduction to organs at risk (OARs), plan complexity, and dose verification accuracy. The goal is to identify the tool that demonstrates superior performance in achieving uniform target dose distribution and reducing OAR dose, while ensuring accurate dose verification.
Methods: Dose uniformity in the planning target volume, excluding the rectum, and dose reduction in the OARs (the rectum and bladder) were assessed.
Isolation and Identification of Mercury-Dissolved Organic Matter Complexes in Mercury-Humic Acid Suspensions.
Rapid Commun Mass Spectrom
April 2025
Department of Civil and Environmental Engineering, Syracuse University, Syracuse, New York, USA.
Rationale: The complexation with dissolved organic matter (DOM) is a pivotal factor influencing transformations, transport, and bioavailability of mercury (Hg) in aquatic environments. However, identifying these complexes poses a significant challenge because of their low concentrations and the presence of coexisting ions.
Methods: In this study, mercury-dissolved organic matter (Hg-DOM) complexes were isolated through solid-phase extraction (SPE) from Hg-humic acid suspensions, and complexes were putatively identified using ultrahigh resolution Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS).
New Library-Based Methods for Nontargeted Compound Identification by GC-EI-MS.
J Am Soc Mass Spectrom
January 2025
Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-8362, United States.
While gas chromatography mass spectrometry (GC-MS) has long been used to identify compounds in complex mixtures, this process is often subjective and time-consuming and leaves a large fraction of seemingly good-quality spectra unidentified. In this work, we describe a set of new mass spectral library-based methods to assist compound identification in complex mixtures. These methods employ mass spectral uniqueness and compound ubiquity of library entries alongside noise reduction and automated comparison of retention indices to library compounds.
View Article and Find Full Text PDF[Serum pharmacochemistry of Panacis Japonici Rhizoma extract based on UPLC-Q-Exactive Orbitrap-MS].
Zhongguo Zhong Yao Za Zhi
December 2024
Thirdgrade Pharmacological Laboratory on Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine, China Three Gorges University Yichang 443002, China College of Medicine and Health Sciences, China Three Gorges University Yichang 443002, China.
In this study, the chemical components of Panacis Japonici Rhizoma extract and absorbed components in rats were identified by ultra-high performance liquid chromatography-quadrupole exactive orbitrap mass spectrometry(UPLC-Q-Exactive Orbitrap-MS). The separation was performed by gradient elution on Waters UPLC BEH C_(18) column(2.1 mm×100 mm, 1.
View Article and Find Full Text PDF[Qualitative and quantitative analysis of chemical components of Dracocephalum moldavica based on UPLC-Q-TOF-MS/MS and UPLC].
Zhongguo Zhong Yao Za Zhi
December 2024
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
Ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry(UPLC-Q-TOF-MS/MS) was used to rapidly identify the chemical components in Dracocephalum moldavica, and UPLC was employed to determine the content of its main components. MS analysis was performed using an electrospray ionization(ESI) source and data were collected in the negative ion mode. By comparing the retention time and mass spectra of reference compounds, and using a self-built compound database and the PubChem database, 68 compounds were identified from D.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!